Patents by Inventor George Sledge

George Sledge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATERIALS AND METHODS FOR IDENTIFYING PATIENTS AT HEIGHTEN RISK FOR DEVELOPING HER2+ RELATED BRAIN TUMORS
    Publication number: 20110269636
    Abstract: Aspects of the invention include methods for identifying patients with HER2+ cancers that are at a heightened risk for developing brain metastasis within three years of having been diagnosed with HER2+ cancer. Some embodiments are methods that include the steps of contacting at least a portion of the tumor tissue from patients with probes that interact with the products of a set of thirteen genes that are expressed in these patients at markedly higher levels than in similarly situated patients that are not a heightened risk for developing brain metastasis within this three year window. In some embodiments the tissue samples are assayed from the presence of RNA indicative of the expression of member of a set of 13 genes identified as being differentially expressed in patients with and without a heightened risk for developing brain metastasis.
    Type: Application
    Filed: November 29, 2010
    Publication date: November 3, 2011
    Applicant: INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION
    Inventors: Sunil Badve, Lang Li, George Sledge, Renata Duchnowaska, Jacek Jassem, Patricia Steeg
  • Gene expression markers for predicting response to chemotherapy
    Publication number: 20050064455
    Abstract: The invention provides sets of genes the expression of which predicts whether cancer patients are likely to have a beneficial treatment response to chemotherapy.
    Type: Application
    Filed: May 24, 2004
    Publication date: March 24, 2005
    Inventors: Joffre Baker, Kathy Miller, Steven Shak, George Sledge, Sharon Soule