Patents by Inventor George Spitalny

George Spitalny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of CR1-binding molecules in clearance and induction of immune responses
    Publication number: 20060263792
    Abstract: The present invention provides methods and compositions related to the discovery of molecules capable of both inducing an immune response to an antigen in a mammal and also effecting clearance of the antigen, with such molecules comprising a first moiety comprising an antigen binding portion which binds specifically to complement receptor 1 (CR1) and does not substantially bind to complement receptor 2 (CR2), linked to a second moiety which comprises the antigen or binds to the antigen. Methods of producing such molecules and their therapeutic and/or prophylactic uses are also featured.
    Type: Application
    Filed: October 31, 2005
    Publication date: November 23, 2006
    Applicant: EluSys Therapeutics, Inc.
    Inventors: Nehal Mohamed, George Spitalny, Leslie Casey, Steven Jones, Steven Pincus
  • Methods and compositions for conversion of antibody activity
    Publication number: 20050031625
    Abstract: The present invention provide a bispecific molecule comprising an antibody that binds a C3b-like receptor linked to one or more non-neutralizing antigen-binding antibodies or fragments thereof. The present invention also provides methods to identify non-neutralizing antibodies, and particularly, to identify enhancing antibodies.
    Type: Application
    Filed: March 29, 2004
    Publication date: February 10, 2005
    Applicant: EluSys Therapeutics, Inc.
    Inventors: Nehal Mohamed, George Spitalny, Leslie Casey
  • Repopulation of macrophages and granulocytes using transforming growth factor-beta
    Patent number: 5147799
    Abstract: Treatment with Transforming Growth Factor-.beta. alone or in combination with a Colony Stimulating Factor therapeutically increases the number of granulocytes and monocyte/macrophages in mammals.
    Type: Grant
    Filed: April 25, 1990
    Date of Patent: September 15, 1992
    Inventors: Isia Bursuker, Joseph A. Carlino, Kim Neddermann, Bernice Schacter, Larry Ellingsworth, George Spitalny