Abstract: Provided herein are drug administration devices, methods, and systems for adjusting drug delivery to a patient to allow drug dosage to be adjusted based on a variety of different factors influencing the patient during administration of the drug. In one embodiment, a drug administration device or system can have a drug holder with a drug therein to be delivered to a patient, one or more sensors that are configured to gather various data associated with the patient, and at least one processor that can analyze the data gathered by the one or more sensors and adjust delivery of the drug based on the data.

Abstract: In general, systems for administering a dmg are provided. In an exemplary embodiment, a dmg administration system includes a dmg administration device configured to communicate with a computer system and at least one sensor configured to obtain sensor data and communicate the sensor data to the drug administration device. The dmg administration device is configured to utilize a first drug dosing scheme when a drug is delivered to a patient, determine a second drug dosing scheme for delivering a drug to the patient dependent on dosing data from the computer system and sensor data collected by the sensor during and/or after the delivery of the first drug according to the first drug dosing scheme, and utilize the second drug dosing scheme when the drug is delivered to the patient.

Abstract: The present disclosure relates to a drug administration device configured to administer a drug. In an exemplary embodiment the drug administration device includes a housing including first and second housing electrical contacts, a dispensing mechanism, a drug holder, a removable power supply including first and second power supply electrical contacts, and at least one protection mechanism in a first protecting configuration when the removable power supply is not received within the housing and in a second configuration when the removable power supply is received within the housing. In another exemplary embodiment the drug administration device includes a housing, a dispensing mechanism disposed within the housing, a removable power supply that is configured to be received within the housing, a sensor configured to determine remaining charge of the removable power supply, and a processor configured to modify operation of the drug administration device in response to data produced by the sensor.

Abstract: The present disclosure relates to drug administration. In an exemplary embodiment, a system can include a drug administration device configured to dispense a drug to a patient, a monitoring device configured to log a delivery event of drug delivery from the drug administration device into the patient, and a sensor configured to sense a patient parameter following delivery of the drug into the patient. In another exemplary embodiment, a drug administration device can include a drug holder configured to hold a drug, a dispensing mechanism configured to dispense the drug, and a sensor configured to sense a patient parameter, and the drug administration device can be configured to locally activate the drug at a target location in the patient. In another exemplary embodiment, methods, devices, and systems are provided to assess when operation of a drug dispensing mechanism is complete and to confirm whether drug administration was successful.

Abstract: A sensor assembly, which may be part of an engine cooling system, senses a condition within an enclosed volume. The sensor assembly includes a mounting structure projecting from a wall of the enclosed volume. The mounting structure includes an opening extending from an exterior of the mounting structure towards the wall and at least one channel extending along an exterior of the mounting structure. The sensor assembly further includes a connector having a sensing portion for sensing the condition within the enclosed volume. A seal seals the enclosed volume at the extension of the connector through the opening. A retaining device has at least one attachment structure that is insertable into the at least one channel. The attachment structure engages the connector such that the connector is non-removable from the mounting structure. An associated method provides the sensor assembly.

Abstract: There is provided embodiments of a fluid fitting, and system incorporating the fluid fitting therein, which is compatible with harsh, caustic environments such as those environments found in the automotive industry. In one embodiment, the fluid fitting can comprise a conductive element with a fluid pathway for transporting a fluid, e.g., fuel. The fluid fitting can also comprise a non-conductive element that is coupled to the conductive element in a manner discharging electrons from the conductive body. The non-conductive element can comprise a cavity with an opening exposing a sensing device with a sensing element disposed on a sensing element housing. The sensing element housing can be sealed to the conductive element, but expose the sensing element to the fluid in the fluid pathway.

Abstract: There is provided embodiments of a fluid fitting, and system incorporating the fluid fitting therein, which is compatible with harsh, caustic environments such as those environments found in the automotive industry. In one embodiment, the fluid fitting can comprise a conductive element with a fluid pathway for transporting a fluid, e.g., fuel. The fluid fitting can also comprise a non-conductive element that is coupled to the conductive element in a manner discharging electrons from the conductive body. The non-conductive element can comprise a cavity with an opening exposing a sensing device with a sensing element disposed on a sensing element housing. The sensing element housing can be sealed to the conductive element, but expose the sensing element to the fluid in the fluid pathway.

Abstract: A fluid quick connector sealingly latches first and second components, one of which has a through bore and the other has a raised bead spaced from a tip end. A retainer is mountable through a transverse bore in one end of the first component and latched to the first component by projections carried on a pair of legs. A flange on the retainer is positioned to engage a surface of the first component to position the retainer on the first component. Inner disposed arms on the retainer engage a constant diameter portion of the second component and resist movement of the raised bead into or out of the bore in the housing when the retainer is in a fully latched position. The flange on the retainer is spaced from the legs of the retainer to enable the legs to be of minimal thickness for a reduced axial length for the retainer.

Abstract: A fluid quick connector sealingly latches first and second components, one of which has a through bore and the other has a raised bead spaced from a tip end. A retainer is mountable through a transverse bore in one end of the first component and latched to the first component by projections carried on a pair of legs. A flange on the retainer is positioned to engage a surface of the first component to position the retainer on the first component. Inner disposed arms on the retainer engage a constant diameter portion of the second component and resist movement of the raised bead into or out of the bore in the housing when the retainer is in a fully latched position. The flange on the retainer is spaced from the legs of the retainer to enable the legs to be of minimal thickness for a reduced axial length for the retainer.

Abstract: A fluid quick connector includes first and second coupled housings having aligned bores. A biased shut off valve is mounted in the first housing and has a seal end normally biased into a fluid flow blocking position; but movable away from the seal upon contact with an end form inserted into the bores to a fluid flow enabling position. The first and second housings interact at an adjustable axial interface formed of mating threads to vary the insertion distance of the endform into the first housing after the endform is latched in the first and second housings by a retainer carried in the second housing, to regulate the fluid flow through the quick connector.

Abstract: A fluid quick connector sealingly latches first and second components, one of which has a through bore and the other has a raised bead spaced from a tip end. A retainer is mountable through a transverse bore in one end of the first component and latched to the first component by projections carried on a pair of legs. A flange on the retainer is positioned to engage a surface of the first component to position the retainer on the first component. Inner disposed arms on the retainer engage a constant diameter portion of the second component and resist movement of the raised bead into or out of the bore in the housing when the retainer is in a fully latched position. The flange on the retainer is spaced from the legs of the retainer to enable the legs to be of minimal thickness for a reduced axial length for the retainer.

Abstract: A quick connector includes a connector housing having a through bore adapted to mate with an endform. An electrical contact is mountable in the bore of the connector housing and includes contact members in the form of projections to provide a secure electrical connection between the endform and the connector housing when the male endform is mounted in the connector housing. In one aspect, the electrical contact is formed as the spacer or top hat in the quick connector housing.

Abstract: An electrically conductive quick connector housing is matable with a conductive male endform. A contact member is carried in the housing to provide a secure electrical connection between the male endform and the housing. In one aspect, the contact member is in the form of at least one projection integrally formed with the housing and extending radially inward into a bore in the housing for engagement with the male endform. In another aspect, the contact member is in the form of at least one longitudinally extending finger projecting unitarily into the bore in the housing. The finger engages the outer diameter of the male endform when the male endform is inserted into the housing.

Abstract: A fluid quick connector sealingly latches first and second components, one of which has a through bore and the other has a raised bead spaced from a tip end. A retainer is mountable through a transverse bore in one end of the first component and latched to the first component by projections carried on a pair of legs. A flange on the retainer is positioned to engage a surface of the first component to position the retainer on the first component. Inner disposed arms on the retainer engage a constant diameter portion of the second component and resist movement of the raised bead into or out of the bore in the housing when the retainer is in a fully latched position. The flange on the retainer is spaced from the legs of the retainer to enable the legs to be of minimal thickness for a reduced axial length for the retainer.

Abstract: A quick connector includes a housing assembly for receiving one end of a conduit with an enlarged annular flange and a retainer for locking the conduit in the housing assembly. The housing assembly includes first and second housings which are rotatably and non-axially displaceably interconnected. A rigid top hat is fixedly mounted in the bore in the first housing to prevent axial displacement of the first and second housings. An annular recess in the top hat receives the flange on the conduit. The housings can also be incrementally indexable ribs on a stem of one housing fixedly and non-rotatingly engage an inner surface of a flexible conduit.

Abstract: A fluid connector includes at least one barb adjacent one end for expanding a flexible conduit thereover. At least one axially and radially extending, non-annular rib is carried on the connector adjacent to the barb. The rib alters the end shape of the flexible conduit into raised and lowered portions which resist rotation of the flexible conduit relative to the connector. The ribs may be employed on any fluid connector, including an adaptor between two fluid conduits, or on a one or two piece fluid quick connector coupling an end form to a flexible conduit.

Abstract: An electrically conductive quick connector housing is matingly engagable with an electrically conductive male endform. An electrically conductive contact member is mounted in the bore of the housing and has an arm extending from a mounting portion which is engagable with the male endform when the male endform is inserted into the housing to electrically connect the male endform to the housing. The mounting portion is in the form of a tubular body or an annular ring. In the case of the annular ring, angular fingers project from the ring for engagement with the housing.

Abstract: An electrically conductive quick connector housing is matable with a conductive male endform. A contact member is carried in the housing to provide a secure electrical connection between the male endform and the housing. In one aspect, the contact member is in the form of at least one projection integrally formed with the housing and extending radially inward into a bore in the housing for engagement with the male endform. In another aspect, the contact member is in the form of at least one longitudinally extending finger projecting unitarily into the bore in the housing. The finger engages the outer diameter of the male endform when the male endform is inserted into the housing.

Abstract: A quick connector includes a connector housing having a through bore adapted to mate with an endform. An electrical contact is mountable in the bore of the connector housing and includes contact members in the form of projections to provide a secure electrical connection between the endform and the connector housing when the male endform is mounted in the connector housing. In one aspect, the electrical contact is formed as the spacer or top hat in the quick connector housing.

Abstract: A release tool for a quick connector with a radially displaceable retainer has a pair of arms extending from a collar which are normally disposed on axially extending surfaces of the housing of the female component of the quick connector when the release tool is mounted on the housing. A retainer engaging surface on each of the arms is movably engageable with projections on side legs of the retainer to urge the projections and the end portions of the side legs of the retainer radially inward to a position where the projections are disengaged from lock edges on the axially extending surfaces of the housing to allow disengagement of the retainer element from the male component of the quick connector.