Patents by Inventor George T. Magnus-Aryitey

George T. Magnus-Aryitey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diaryl ether derivatives and uses thereof
    Patent number: 7618996
    Abstract: Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. where R1, R2, R3, R4, R5, and R6 are described herein.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: November 17, 2009
    Assignee: Pfizer Inc.
    Inventors: Roger B. Ruggeri, George T. Magnus-Aryitey
  • Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof
    Patent number: 7615651
    Abstract: Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. where R, R1, R2a, R2b, R3, R4, V, R6, R7, R8, R9, W and X are described herein.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: November 10, 2009
    Assignee: Pfizer Inc.
    Inventors: Roger B. Ruggeri, George T. Magnus-Aryitey, Benjamin A. Thuma
  • Diaryl, Dipyridinyl and Aryl-Pyridinyl Derivatives and Uses Thereof
    Publication number: 20080167371
    Abstract: Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. where R, R1, R2a, R2b, R3, R4, V, R6, R7, R8, R9, W and X are described herein.
    Type: Application
    Filed: November 13, 2007
    Publication date: July 10, 2008
    Inventors: Roger B. Ruggeri, George T. Magnus-Aryitey, Benjamin Aaron Thuma
  • 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
    Patent number: 6906082
    Abstract: Cholesteryl ster transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: June 14, 2005
    Assignee: Pfizer Inc.
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester
  • 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
    Publication number: 20040092550
    Abstract: Cholesteryl ster transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain oth r plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 13, 2004
    Applicant: Pfizer Inc.
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester
  • 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
    Patent number: 6586448
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: July 1, 2003
    Assignee: Pfizer Inc.
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester
  • 4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinolines
    Patent number: 6489478
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: December 3, 2002
    Assignee: Pfizer Inc.
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester
  • 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
    Patent number: 6197786
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: March 6, 2001
    Assignee: Pfizer Inc
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester
  • 4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinolines
    Patent number: 6140343
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: October 31, 2000
    Assignee: Pfizer
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester