Patents by Inventor George Themelis

George Themelis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250060576
    Abstract: Examples relate to a microscope system, such as a surgical microscope system, and to a corresponding method. The microscope system (100) comprises a microscope (120) with a first optical imaging sensor (122) for generating first imaging sensor data based on light having a first wavelength spectrum, a second optical imaging sensor (124) for generating second imaging sensor data based on light having a second wavelength spectrum, and a multispectral iris (130), configured to provide an opening with a first numerical aperture for the light having the first wavelength spectrum and an opening with a second numerical aperture for the light having the second wavelength spectrum, with the first numerical aperture being different from the second numerical aperture. The microscope system comprises one or more processors (114), configured to generate a composite image based on the first imaging sensor data and based on the second imaging sensor data.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 20, 2025
    Inventor: George THEMELIS
  • Publication number: 20250052995
    Abstract: Examples relate to an optical imaging system (100), such as a microscope system (100), and to a corresponding method. The optical imaging system (100) comprises an optical imaging component (120) with (124), the optical imaging component being suitable for imaging an object (10). The optical imaging system (100) comprises an illumination system (130) for emitting light having a polarization towards the object. The optical imaging system (100) comprises a polarization filter (140) configured to block light having the polarization from arriving at the first optical imaging sensor. The optical imaging system (100) comprises a processing system (110) being configured to obtain first imaging sensor data from the first optical imaging sensor and second imaging sensor data from the second optical imaging sensor, and generate a composite view based on the first imaging sensor data and based on the second imaging sensor data.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Inventor: George THEMELIS
  • Publication number: 20250021163
    Abstract: A human system interface (HSI) for contactlessly controlling a device for a medical procedure is configured to generate a control space, measure a position of a user in the control space, provide a first contactless haptic stimulus in the control space to the user based on the measured position, measure a contactless haptic input from the user in the control space, provide a second haptic stimulus to the user depending on the contactless haptic input, and, based on the contactless haptic input, change a parameter of the HSI and/or provide a parameter to the device connected to the HSI.
    Type: Application
    Filed: July 2, 2024
    Publication date: January 16, 2025
    Inventor: George THEMELIS
  • Publication number: 20250006348
    Abstract: Examples relate to a system (110), a method, and a computer program for a imaging device (120) of a surgical imaging system (100), and to a corresponding surgical imaging system comprising such a system. The system is configured to determine a first set of settings being suitable for using the imaging device in a surgical procedure. The system is configured to determine a second set of settings currently being used. The system is configured to provide a signal indicating a difference between the first and second set of settings. The signal comprises information on at least one setting to adjust to obtain the first set of settings.
    Type: Application
    Filed: October 27, 2022
    Publication date: January 2, 2025
    Inventor: George THEMELIS
  • Publication number: 20240427132
    Abstract: An optical imaging system comprises optical imaging sensor(s) for providing imaging sensor data of an object to be imaged. The optical imaging system comprises a diode-based illumination system for emitting a first unit of light beam(s) having a first polarization and a second unit of light beam(s) having a second polarization towards the object. The optical imaging system comprises a processing system to generate a digital image representation of the object, comprising controlling a contribution of the at least two units of light beams in a digital image representation of the object, by at least one of a) controlling, separately for each of the at least two units, the light emitted by the unit, and b) controlling, separately for each of the at least two polarizations emitted by the at least two units, a contribution of the light having the respective polarization in the digital image representation of the object.
    Type: Application
    Filed: June 19, 2024
    Publication date: December 26, 2024
    Inventor: George THEMELIS
  • Patent number: 12156769
    Abstract: Examples relate to a surgical microscope system and a corresponding apparatus, method and computer program. The surgical microscope system comprises one or more sensors for providing sensor information about a balance of the surgical microscope system. The surgical microscope system comprises one or more brakes for holding at least one component of the surgical microscope system in place. The surgical microscope system comprises a surgical microscope. The surgical microscope system comprises a processing module, configured to process the sensor information. The processing module is configured to determine an information about the balance of the surgical microscope system. In some embodiments, the processing module is configured to provide a warning to a user of the surgical microscope system based on the information about the balance of the surgical microscope system. The warning indicates danger of imbalance in the surgical microscope system.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: December 3, 2024
    Assignee: Leica Instruments (Singapore) Pte Ltd.
    Inventor: George Themelis
  • Patent number: 12150720
    Abstract: The present invention relates to a surgical microscope with a field of view and comprising an optical imaging system which images an inspection area which is at least partially located in the field of view, and to a method for a gesture control of a surgical microscope having an optical imaging system. The surgical microscope further comprises a gesture detection unit for detection of a movement of a surgical instrument, the gesture detection unit having a detection zone which is located between the inspection area and the optical imaging system and is spaced apart from the inspection area, and the gesture detection unit being configured to output a control signal to the optical imaging system depending on the movement of the surgical instrument in the detection zone, the optical imaging system being configured to alter its state depending on the control signal.
    Type: Grant
    Filed: July 17, 2023
    Date of Patent: November 26, 2024
    Assignee: LEICA INSTRUMENTS (SINGAPORE) PTE. LTD.
    Inventor: George Themelis
  • Publication number: 20240385424
    Abstract: Examples relate to an apparatus for an optical imaging system. The apparatus comprises one or more processors and one or more storage devices. The apparatus is configured to obtain position data indicative of a position of the microscope of the optical imaging system relative to the user of the optical imaging system. The apparatus is further configured to determine control data for adjusting an optical path of the microscope. The control data is determined based on the position data.
    Type: Application
    Filed: May 15, 2024
    Publication date: November 21, 2024
    Inventor: George THEMELIS
  • Patent number: 11978199
    Abstract: Examples relate to an optical system and to an apparatus, method and computer program for an optical system. The optical imaging system comprises a camera for providing a camera image of a surface of an object. The optical imaging system further comprises one or more measurement modules for performing one or more measurements at one or more points of the surface of the object. The optical imaging system further comprises a display module. The optical imaging system further comprises a processing module configured to obtain the camera image of the surface of the object from the camera. The processing module is configured to obtain the one or more measurements at the one or more points of the surface of the object from the one or more measurement modules. The processing module is configured to determine a spatial location of the one or more points of the surface relative to the camera image.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: May 7, 2024
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventor: George Themelis
  • Patent number: 11921275
    Abstract: The present invention relates to an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, such as a surgical microscope, in particular a surgical multispectral fluorescence microscope, comprising a first optical filter (35). The present invention also relates to an observation system (3) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope, comprising a beam splitter (21) adapted to split a light image (13) into a first light portion (16, 17) along a first light path (18) and a second light portion (20) along a second light path (19).
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: March 5, 2024
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventors: Manfred Kuster, George Themelis
  • Patent number: 11857164
    Abstract: The invention relates to a method, an image processor (26) and a medical observation device (1), such as a microscope or endoscope, for observing an object (4) containing a bolus of at least one fluorophore (12). The object (4) is preferably live tissue comprising several types (16, 18, 20) of tissue. According to the method, a set (34) of component signals (36) is provided. Each component signal (36) represents a fluorescence intensity development of the fluorophore (12) over time in a different type of tissue. A time series (8) of input frames (10) is accessed, one input frame (10) after the other. The input frames (10) represent electronically coded still images of the object (4) at subsequent time. Each input frame (10) contains at least one observation area (22) comprising at least one pixel (23).
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: January 2, 2024
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventor: George Themelis
  • Publication number: 20230355323
    Abstract: The present invention relates to a surgical microscope with a field of view and comprising an optical imaging system which images an inspection area which is at least partially located in the field of view, and to a method for a gesture control of a surgical microscope having an optical imaging system. The surgical microscope further comprises a gesture detection unit for detection of a movement of a surgical instrument, the gesture detection unit having a detection zone which is located between the inspection area and the optical imaging system and is spaced apart from the inspection area, and the gesture detection unit being configured to output a control signal to the optical imaging system depending on the movement of the surgical instrument in the detection zone, the optical imaging system being configured to alter its state depending on the control signal.
    Type: Application
    Filed: July 17, 2023
    Publication date: November 9, 2023
    Inventor: George THEMELIS
  • Patent number: 11800980
    Abstract: The invention relates to an augmented reality surgical microscope (1) having a camera (2), preferably a multispectral or hyperspectral camera. The augmented reality surgical microscope (1) retrieves input image data (22) of an object (8) comprising in particular live tissue (10). The input image data (22) comprise visible-light image data (26) as well as fluorescent-light image data (24) of at least one fluorophore (14). The augmented reality surgical microscope (1) permits the automatic identification and marking in pseudo-color (86) of various types of vascular plexus structures (54a 54b, 54c) and/or of blood flow direction (56) depending on the fluorescent-light image data (24). A pre-operative three-dimensional atlas (36) and/or ultrasound image data (39) may be elastically matched to the visible-light image data (26). The augmented reality surgical microscope (1) allows different combinations of the various image data to be output simultaneously to different displays (75).
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: October 31, 2023
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventor: George Themelis
  • Patent number: 11744653
    Abstract: The present invention relates to a surgical microscope with a field of view and comprising an optical imaging system which images an inspection area which is at least partially located in the field of view, and to a method for a gesture control of a surgical microscope having an optical imaging system. The surgical microscope further comprises a gesture detection unit for detection of a movement of a surgical instrument, the gesture detection unit having a detection zone which is located between the inspection area and the optical imaging system and is spaced apart from the inspection area, and the gesture detection unit being configured to output a control signal to the optical imaging system depending on the movement of the surgical instrument in the detection zone, the optical imaging system being configured to alter its state depending on the control signal.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: September 5, 2023
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventor: George Themelis
  • Publication number: 20230248464
    Abstract: Examples relate to a surgical microscope system, and to a system, a method, and a computer program for a microscope of a surgical microscope system. The system is configured to the system is configured to obtain imaging sensor data from at least one optical imaging sensor of the microscope. The system is configured to determine information on an area of interest of a user of the surgical microscope system based on an input of the user. The system is configured to determine an anatomical feature of interest within the area of interest. The system is configured to detect a position of the anatomical feature of interest within the imaging sensor data. The system is configured to trigger an autofocus functionality of the microscope to focus on the position of the anatomical feature of interest.
    Type: Application
    Filed: February 8, 2023
    Publication date: August 10, 2023
    Inventor: George THEMELIS
  • Publication number: 20230217120
    Abstract: Examples relate to systems, methods and computer programs for a microscope system and for determining a transformation function, and to a corresponding microscope system. The system for the microscope system comprises one or more processors and one or more storage devices. The system is configured to obtain first imaging sensor data from a first imaging sensor of a microscope of the microscope system and second imaging sensor data from a second imaging sensor of the microscope, the first imaging sensor data comprises sensor data on light sensed in a first plurality of mutually separated wavelength bands. The second imaging sensor data comprises sensor data on light sensed in a second plurality of mutually separated wavelength bands. The wavelength bands of the first plurality of mutually separated wavelength bands or of the second plurality of mutually separated wavelength bands are wavelength bands that are used for fluorescence imaging.
    Type: Application
    Filed: March 8, 2021
    Publication date: July 6, 2023
    Inventors: George THEMELIS, Tobias WILKEN
  • Publication number: 20230190402
    Abstract: Examples relate to a system, method, and computer program for a surgical microscope system, and to a corresponding surgical microscope system. The system is configured to determine a depth characteristic of a surgical site being imaged using a microscope. The system is configured to adjust a numerical aperture of the microscope based on the depth characteristic of at least a portion of the surgical site.
    Type: Application
    Filed: December 20, 2022
    Publication date: June 22, 2023
    Inventor: George THEMELIS
  • Patent number: 11663716
    Abstract: Examples relate to an optical imaging system, and to a corresponding apparatus, method and computer program for an optical imaging system. The optical imaging system comprises one or more information sources for providing information about a current orientation of the optical imaging system towards at least a part of an object of interest. The optical imaging system comprises one or more output modules for providing guidance information for a user of the optical imaging system. The optical imaging system comprises a processing module configured to determine information on a desired orientation of the optical imaging system towards at least a part of the object of interest.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: May 30, 2023
    Assignee: LEICA INSTRUMENTS (SINGAPORE) PTE., LTD.
    Inventor: George Themelis
  • Publication number: 20230137862
    Abstract: Examples relate to a system, a method, and a computer program for a microscope of a surgical microscope system. The system configured to obtain imaging sensor data from at least one optical imaging sensor of the microscope. The imaging sensor data comprises a first component that is based on reflectance imaging and a second component that is based on fluorescence imaging. The system is configured to generate a digital view of a surgical site based on at least the first component of the imaging sensor data. The system is configured to detect at least one feature of interest in the second component of the imaging sensor data and generate a visual indicator of the at least one feature of interest. The system is configured to provide a display signal to a display device of the surgical microscope system, the display signal comprising the digital view and the visual indicator.
    Type: Application
    Filed: October 26, 2022
    Publication date: May 4, 2023
    Inventor: George THEMELIS
  • Patent number: 11588986
    Abstract: Examples relate to apparatuses, methods and computer programs for a microscope system, more specifically, but not exclusively, to the use of two optical imaging modules to obtain image data having a first and a second field of view. The apparatus comprises an interface. The interface is suitable for obtaining first image data of a sample from a first optical imaging module. The first image data has a first field of view. The interface is suitable for obtaining second image data of the sample from a second optical imaging module. The second image data has a second field of view. The first field of view comprises the second field of view. The apparatus comprises a processing module. The processing module is configured to generate an image output signal for a display of the microscope system. In some embodiments, the processing module is configured to process the first image data to detect an abnormality outside the second field of view.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: February 21, 2023
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventor: George Themelis