Patents by Inventor George Topolov

George Topolov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
    Patent number: 8088766
    Abstract: Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Methods of treating hyperproliferative diseases in mammals are also disclosed.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: January 3, 2012
    Assignee: Array BioPharma Inc.
    Inventors: Eli Wallace, George Topolov, Qian Zhao, Joseph P. Lyssikatos
  • Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
    Patent number: 7488823
    Abstract: Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Methods of treating hyperproliferative diseases in mammals are also disclosed.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: February 10, 2009
    Assignee: Array Biopharma, Inc.
    Inventors: Eli Wallace, George Topolov, Qian Zhao, Joseph P. Lyssikatos
  • CYANOGUANIDINES AND CYANOAMIDINES AS ERBB2 AND EGFR INHIBITORS
    Publication number: 20090012290
    Abstract: Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Methods of treating hyperproliferative diseases in mammals are also disclosed.
    Type: Application
    Filed: September 12, 2008
    Publication date: January 8, 2009
    Applicant: ARRAY BIOPHARMA, INC.
    Inventors: Eli Wallace, George Topolov, Qian Zhao, Joseph P. Lyssikatos
  • Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
    Publication number: 20050101617
    Abstract: Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Methods of treating hyperproliferative diseases in mammals are also disclosed.
    Type: Application
    Filed: November 10, 2003
    Publication date: May 12, 2005
    Inventors: Eli Wallace, George Topolov, Qian Zhao, Joseph Lyssikatos