Patents by Inventor George Tora

George Tora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NK-1 AND SEROTONIN TRANSPORTER INHIBITORS
    Publication number: 20070249607
    Abstract: The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.
    Type: Application
    Filed: April 13, 2007
    Publication date: October 25, 2007
    Inventors: Andrew Degnan, Kevin Gillman, Derek Denhart, Jonathan Ditta, Ramkumar Rajamani, Ying Han, George Tora
  • ANTI-MIGRAINE TREATMENTS
    Publication number: 20070232600
    Abstract: The present invention relates to methods of treating neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors using pharmaceutical compositions comprising compounds of Formula (I)
    Type: Application
    Filed: January 5, 2007
    Publication date: October 4, 2007
    Inventors: Ling Chen, Prasad Chaturvedula, Rita Civiello, Andrew Degnan, Gene Dubowchik, Xiaojun Han, Xiang Jun Jiang, George Karageorge, Guanglin Luo, John Macor, Graham Poindexter, George Tora
  • ANTI-MIGRAINE SPIROCYCLES
    Publication number: 20070149503
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 28, 2007
    Inventors: PRASAD CHATURVEDULA, Ling Chen, Rita Civiello, Andrew Degnan, Gene Dubowchik, Xiaojun Han, Xiang Jun Jiang, John Macor, Graham Poindexter, George Tora, Guanglin Luo
  • Calcitonin gene related peptide receptor antagonists
    Patent number: 7220862
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: May 22, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Prasad V. Chaturvedula, Ling Chen, Rita Civiello, Andrew P. Degnan, Gene M. Dubowchik, Xiaojun Han, Xiang Jun J. Jiang, George N. Karageorge, Guanglin Luo, John E. Macor, Graham Poindexter, George Tora
  • Heterocyclic anti-migraine agents
    Publication number: 20050153959
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: December 3, 2004
    Publication date: July 14, 2005
    Inventors: Guanglin Luo, Ling Chen, Andrew Degnan, Gene Dubowchik, John Macor, George Tora, Prasad Chaturvedula
  • Calcitonin gene related peptide receptor antagonists
    Publication number: 20040204397
    Abstract: The present invention relates to compounds of Formula (I) 1
    Type: Application
    Filed: December 5, 2003
    Publication date: October 14, 2004
    Inventors: Prasad V. Chaturvedula, Ling Chen, Rita Civiello, Charles Mark Conway, Andrew P. Degnan, Gene M. Dubowchik, Xiaojun Han, Xiang Jun J. Jiang, George N. Karageorge, Guanglin Luo, John E. Macor, Graham Poindexter, George Tora, Shikha Vig