Patents by Inventor George Ueda

George Ueda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220072120
    Abstract: Nanoparticles and vaccines containing these nano particles that elicit an immune response against hemagglutinin (HA) proteins from a broad range of influenza viruses are provided. The nanoparticles are made from self-assembling proteins, at least one of which is joined to an immunogenic portion of an influenza HA protein. This immunogenic portion is displayed on the nanoparticle surface, making the nanoparticles useful for vaccinating subjects against influenza virus.
    Type: Application
    Filed: February 7, 2020
    Publication date: March 10, 2022
    Inventors: Masaru Kanekiyo, Barney S. Graham, Seyhan Boyoglu-Barnum, Rebecca A. Gillespie, Neil P. King, Daniel Ellis, Jing Yang Wang, George Ueda, Jorge Fallas
  • Publication number: 20210363214
    Abstract: De novo designed multi-pass transmembrane polypeptides are described, that include 2 or more transmembrane domains that are each between 15 and 35 amino acids in length, include one or more polar residues, and include at least 60%, 65%, 70%, 75%, 80%, 85%, 90%, or more hydrophobic amino acid residues.
    Type: Application
    Filed: February 28, 2019
    Publication date: November 25, 2021
    Inventors: Peilong LU, David BAKER, Scott BOYKEN, Zibo CHEN, Jorge FALLAS, George UEDA, William H. SHEFFLER
  • Publication number: 20210183465
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Application
    Filed: September 22, 2020
    Publication date: June 17, 2021
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • Publication number: 20200397886
    Abstract: The present disclosure provides nanostructures and nanostructure-based vaccines. Some nanostructures of the present disclosure display antigens capable of eliciting immune responses to infectious agents such as bacteria, viruses, and pathogens. Some vaccines of the present disclosure are useful for preventing or decreasing the severity of infection with an infectious agent, including, for example and without limitation, lyme disease, pertussis, herpes virus, orthomyxovirus, paramyxovirus, pneumovirus, filovirus, flavivirus, reovirus, retrovirus, meningococcus, or malaria. The antigens may be attached to the core of the nanostructure either non-covalently or covalently, including as a fusion protein or by other means disclosed herein. Multimeric antigens may optionally be displayed along a symmetry axis of the nanostructure. Also provided are proteins and nucleic acid molecules encoding such proteins, vaccine compositions, and methods of administration.
    Type: Application
    Filed: February 28, 2019
    Publication date: December 24, 2020
    Inventors: Neil KING, David BAKER, Lance STEWART, Brooke FIALA, Daniel ELLIS, Lauren CARTER, Rashmi RAVICHANDRAN, George UEDA, Jorge FALLAS, Una NATTERMAN
  • Patent number: 10818377
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: October 27, 2020
    Assignee: University of Washington
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • Publication number: 20190155988
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 23, 2019
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • Publication number: 20180137234
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 17, 2018
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen