Patents by Inventor George Vlasuk

George Vlasuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
    Publication number: 20240091184
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: May 1, 2023
    Publication date: March 21, 2024
    Inventors: Eddine SAIAH, George VLASUK
  • Modulators of Sestrin-GATOR2 interaction and uses thereof
    Patent number: 11679090
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: June 20, 2023
    Assignee: Navitor Pharmaceuticals, Inc.
    Inventors: Eddine Saiah, George Vlasuk
  • MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
    Publication number: 20210228523
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 30, 2020
    Publication date: July 29, 2021
    Inventors: Eddine SAIAH, George VLASUK
  • Modulators of Sestrin-GATOR2 interaction and uses thereof
    Patent number: 10912750
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: February 9, 2021
    Assignee: NAVITOR PHARMACEUTICALS, INC.
    Inventors: Eddine Saiah, George Vlasuk
  • MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
    Publication number: 20180333381
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: April 25, 2018
    Publication date: November 22, 2018
    Inventors: Eddine Saiah, George Vlasuk
  • Inhibitors Of PAI-1 For Treatment Of Muscular Conditions
    Publication number: 20070203220
    Abstract: This invention describes novel methods of treating muscle damage, muscle wasting, muscle degeneration, muscle atrophy or reduced rates of muscle repair associated with various conditions such as muscular dystrophy, through the use of small-molecule PAI-1 inhibitors.
    Type: Application
    Filed: February 26, 2007
    Publication date: August 30, 2007
    Applicant: Wyeth
    Inventors: David Crandall, George Vlasuk
  • Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor
    Publication number: 20070010449
    Abstract: The present invention provides methods of treating hemorrhagic fevers where selective inhibitors of fVIIa/TF are used as a treatment for hemorrhagic fevers and have therapeutic effects which include ameliorating and/or preventing coagulopathy and inflammatory responses. These inhibitors include certain proteins which are part of a family termed Nematode-Extracted Anticoagulant Proteins (“NAPs”). Other inhibitors include Tissue Factor Pathway Inhibitor (“TFPI”) and TFPI analogs.
    Type: Application
    Filed: September 12, 2006
    Publication date: January 11, 2007
    Applicant: Dendreon Corporation
    Inventor: George Vlasuk
  • Nematode-extracted serine protease inhibitors and anticoagulant proteins
    Publication number: 20060246547
    Abstract: Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can be isolated from natural sources as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.
    Type: Application
    Filed: June 14, 2006
    Publication date: November 2, 2006
    Inventors: George Vlasuk, Patrick Stanssens, Joris Messens, Marc Lauwereys, Yves LaRoche, Laurent Jespers, Yannick Gansemans, Matthew Moyle, Peter Bergum
  • Nematode-extracted serine protease inhibitors and anticoagulant proteins
    Publication number: 20050191724
    Abstract: Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can be isolated from natural sources as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.
    Type: Application
    Filed: March 29, 2005
    Publication date: September 1, 2005
    Inventors: George Vlasuk, Patrick Stanssens, Joris Messens, Marc Lauwereys, Yves LaRoche, Laurent Jespers, Yannick Gansemans, Matthew Moyle, Peter Bergum