Abstract: Imidazo[4,5-c]quinoline compounds having a substituent that is attached at the N-1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.

Abstract: A method for deriving seismic information from over a relatively large expanse of land to determine relevant strike, dip, velocity and related information. The method consists of the utilization of a plurality of strike, dip, velocity (SDV) cross patterned source-receiver arrays disposed at spaced known locations over a selected terrain, thereafter to derive localized and offset seismic data relative to selected pairs or groups of the SDV cross patterns with further signal processing to smooth and integrate strike, dip and velocity information over a specific substratum. The method utilizes information as derived from each SDV cross pattern, as well as offset seismic signal information derived from source/receiver combinations spanning two selected SDV cross patterns.

Abstract: Method and apparatus for concurrently and interactively displaying a selected plurality of measurable properties of geophysical data to empirically derive the best combined presentation of the selected attribute properties for interpretation. The technique of the present invention allows the interpreter to more easily comprehend simultaneous variation of several geophysical data attributes and to relate the effects to a specific end result for the geophysical indicators of interest. In accordance with the method, the one or more geophysical attribute variables are quantified and then rasterized so that the data is represented as a gridded variable area display wherein color intensity of the grid units is some function of the instantaneous variable. The resulting data is then loaded into digital refresh memory of an image processing computer whereupon it us interactively mixed for analysis in accordance with operator selected colors and color intensity weighting.

Abstract: A method for deriving seismic information of more generalized nature over a relatively large and previously unexplored expanse of land to determine relevant strike, dip, velocity and related information. The method consists of the placing of a plurality of seismic sources and receivers in respective lines arranged in a cross pattern, each line being generally at right angles each to the other, and thereafter exciting the sources and recording the received energy for further processing to derive the strike, dip and velocity information for selected strata by using travel times of signal return.

Abstract: A method for deriving seismic information from over a relatively large expanse of land to determine relevant strike, dip, velocity and related information. The method consists of the utilization of a plurality of strike, dip, velocity (SDV) cross patterned source-receiver arrays disposed at spaced known locations over a selected terrain, thereafter to derive localized and offset seismic data relative to selected pairs of groups of the SDV cross patterns with further signal processing to smooth and integrate strike, dip and velocity information over a specific substratum. The method utilizes information as derived from each SDV cross pattern, as well as offset seismic signal information derived from source/receiver combinations spanning two selected SDV cross patterns.