Patents by Inventor George Walter Koszalka

George Walter Koszalka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR THE TREATMENT OF NEUROLOGIC DISORDERS
    Publication number: 20140275060
    Abstract: Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of certain neurologic disorders, including disorders related to NMDA receptor activity, including neuropsychiatric disorders, neurodegenerative disorders and other neurologic diseases, disorders and conditions including stroke, brain injury, epilepsy, neuropsychiatric disorders, mood disorders, chronic pain and related conditions.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: David Steven Menaldino, George Walter Koszalka, Ruppa Poornachary Kamalesh Babu, Scott James Myers
  • Modified Peptides and Uses Thereof
    Publication number: 20120142601
    Abstract: The invention includes compounds that are useful in treating perioperative shivering or temperature spiking, lowering body temperature, treating psychosis or treating pain. The invention also includes methods for treating perioperative shivering or temperature spiking, lowering body temperature, treating psychosis or treating pain in a subject in need thereof.
    Type: Application
    Filed: July 20, 2011
    Publication date: June 7, 2012
    Inventors: George Walter Koszalka, Justin Orion Brower
  • Therapeutic compounds
    Patent number: 6617315
    Abstract: The present invention relates to benzimidazole derivatives and their use in medical therapy particularly for the treatment or prophylaxis of restenosis.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: September 9, 2003
    Inventors: Stanley Dawes Chamberlain, George Walter Koszalka, Jeffrey H. Tidwell, Nanine Agneta Vandraanen
  • Therapeutic compounds
    Publication number: 20010003744
    Abstract: The present invention relates to benzimidazole derivatives and their use in medical therapy particularly for the treatment or prophylaxis of virus infections such as those caused by herpes viruses. The invention also relates to the preparation of the benzimidazole derivatives and pharmaceutical formulations containing them.
    Type: Application
    Filed: December 14, 2000
    Publication date: June 14, 2001
    Inventors: Stanley Dawes Chamberlain, Susan Mary Daluge, George Walter Koszalka
  • L-benzimidazole nucleosides
    Patent number: 6204249
    Abstract: The present invention relates to benzimidazole derivatives and their use in medical therapy particularly for the treatment or prophylaxis of virus infections such as those caused by herpes viruses. The invention also relates to the preparation of the benzimidazole derivatives and pharmaceutical formulations containing them.
    Type: Grant
    Filed: July 13, 1998
    Date of Patent: March 20, 2001
    Assignee: Glaxo Wellcome Inc.
    Inventors: Stanley Dawes Chamberlain, George Walter Koszalka, Jeffrey H. Tidwell, Nanine Agneta Vandraanen
  • Antiviral benzimidazole nucleoside analogues and a method for their preparation
    Patent number: 6077832
    Abstract: The present invention relates to benzimidazole derivatives and their use in medical therapy particularly for the treatment or prophylaxis of virus infections such as those caused by herpes viruses. The invention also relates to the preparation of the benzimidazole derivatives and pharmaceutical formulations containing them.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: June 20, 2000
    Assignee: Glaxo Wellcome Inc.
    Inventors: Stanley Dawes Chamberlain, Susan Mary Daluge, George Walter Koszalka
  • Antiviral benzimidazole nucleoside analogues and method for their preparation
    Patent number: 5998605
    Abstract: The present invention relates to benzimidazole derivatives and their use in medical therapy particularly for the treatment or prophylaxis of virus infections such as those caused by herpes viruses. The invention also relates to the preparation of the benzimidazole derivatives and pharmaceutical formulations containing them.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: December 7, 1999
    Assignee: Glaxo Wellcome Inc.
    Inventors: Stanley Dawes Chamberlain, Susan Mary Daluge, George Walter Koszalka
  • Tumor treatment with arabinofuranosyl purine derivatives
    Patent number: 5821236
    Abstract: 6-Alkoxy derivatives of Ara-G, and pharmaceutically acceptable esters thereof, are described as being useful in tumor therapy. Novel pharmaceutically acceptable esters, their preparation and pharmaceutical formulations containing them are also disclosed.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: October 13, 1998
    Assignee: Glaxo Wellcome Inc.
    Inventors: Thomas Anthony Krenitsky, Devron Randolph Averett, George Walter Koszalka
  • Therapeutic methods for using ARA-G derivatives
    Patent number: 5747472
    Abstract: 6-Alkoxy derivatives of Ara-G, and pharmaceutically acceptable esters thereof, are described as being useful in tumour therapy. Novel pharmaceutically acceptable esters, their preparation and pharmaceutical formulations containing them are also disclosed.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 5, 1998
    Assignee: Glaxo Wellcome Inc.
    Inventors: Thomas Anthony Krenitsky, Devron Randolph Averett, George Walter Koszalka, Gerald Wolberg
  • 2',3'-dideoxy-3'-fluoro-purine ribonucleosides
    Patent number: 5663154
    Abstract: 2',3'-Dideoxy-3'-fluoro-(B-D-ribofuranosyl) purine nucleosides possessing the ability to inhibit hepatitis B and HIV viral infections.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: September 2, 1997
    Assignee: Glaxo Wellcome Inc.
    Inventors: Charlene Louise Burns, George Walter Koszalka, Thomas Anthony Krenitsky