Abstract: A circuit is set up for a container or vessel (10) as shown in FIG. 1, which has a microphone (20), a speaker (30), a frequency control device (40) volume control device (50), an amplifier (60), a frequency reader (70) and a spectrum analyzer (80). The oscillation in the circuit is created by applying power to the amplifier (60) which creates an initial fixed standing wave that does not move. Adjusting or changing components, invokes a new behavior of the circuit which is parasitic in nature and reading of oscillating frequency on the frequency reader (70) determines the change of conditions inside the vessel or container. The method is non-intrusive, and the method of this invention can also be used for measurement of miniscule quantities in microns or micro liters such as that of biofilm or algal growth.

Abstract: A circuit is set up for a container or vessel (10) as shown in FIG. 1, which has a microphone (20), a speaker (30), a frequency control device (40) volume control device (50), an amplifier (60), a frequency reader (70) and a spectrum analyzer (80). The oscillation in the circuit is created by applying power to the amplifier (60) which creates an initial fixed standing wave that does not move. Adjusting or changing components, invokes a new behavior of the circuit which is parasitic in nature and reading of oscillating frequency on the frequency reader (70) determines the change of conditions inside the vessel or container. The method is non-intrusive, and the method of this invention can also be used for measurement of miniscule quantities in microns or micro liters such as that of biofilm or algal growth.

Abstract: The present invention concerns the use of protein biomarkers for use in facilitating in the prognosis and/or treatment regime of bladder cancer. In particular, the invention relates to the use of shed protein fragments, such as fragments of Epithelial cell adhesion molecule (EpCAM) and/or epidermal growth factor receptor (EGFR) detected in a sample of urine, as biomarkers for use in facilitating the prognosis and/or treatment regime of urothelial bladder cancer.

Abstract: An improved bicycle rack for public and private use having a hanger housing frame (10), having a hinged door extending from the upper portion of the housing, connected with a hinge assembly (13). Extending from the lower frame end is a seats section, (26), (27), (28), (29), allowing the placing a bicycle frame and one or two bicycle tires. A flange (18) protrudes through a flange cutout (20) when the door (17) is closed. The flange (18) has a primary shackle cutout (19) providing for the locking of the chamber opening (16), no longer requiring the use of u-shape, tether locks, (although they may be used) a simple key or combination lock is all that is required to lock the frame and released tires within an approximately 9?×9? chamber (25). The hanger housing mounting surface (24) is intended to be welded or otherwise affixed to parking meters, stationary objects, and other similar structures.

Abstract: A method is provided for reducing an immune response to an allergen or antigenic determinant thereof in a mammal by administering a modulator of the Notch signalling pathway.

Abstract: Conjugates comprising a plurality of modulators of the Notch signalling pathway chemically bound to a support structure are described. The conjugates are useful for modulation of the Notch signalling pathway and treatment of associated conditions.

Abstract: A method is disclosed for therapeutic modulation of Notch signalling by administering a construct comprising a multiplicity of bond, linked or immobilised modulators of Notch signalling.

Abstract: A method for detecting modulators of Notch signalling is described. The method includes the step of monitoring Notch signalling in a cell of the immune system in the presence of a candidate modulator.

Abstract: In accordance with this invention are methods for making the novel compositions and methods of using the compositions for polymerization of olefins. In its broadest form, the method of producing the supported catalytic composition of the present invention comprises treating an inorganic or inorganic oxide support which has incorporated uniformly therein a Group 3-10 transition metal from the Periodic Table with a metal alkylating reagent wherein the reaction product is then treated with a halogenating reagent. The resultant reaction product can be recovered and is available for use in conjunction with the activating co-catalyst for the polymerization of polyolefins.

Abstract: Disclosed is a personalized, network-based, distributed learning system. The system allows for the dynamic creation of teaching materials personally tailored for the needs of the individual striving to learn the material. The system additionally allows for learning assessment of the student's comprehension of the course material, and dynamic creation of additional course material representing a portion of the course material not comprehended by the student. Additionally disclosed are methods for caching course content and developing a course curriculum for educating a student about the course material.

Abstract: The present invention is directed to a supported catalytic activator composition resulting from the contact of a catalyst support (formed by reaction of a carrier, such as an inorganic oxide (e.g., silica) and an organo halide such as bromo pentafluorobenzene in the presence of base) and a catalytic activator such as dimethylanilinium tetrakis (pentafluorophenyl) borate, and methods for making the same.

Abstract: The present invention is directed to a supported catalyst composition resulting from contact of at least one transition metal catalyst precursor, such as a metallocene catalyst, and a support activator composition resulting from contact of a catalyst support (formed by reaction of a carrier, for example, an inorganic oxide (e.g., silica) and an organo halide such as bromo pentaflurobenzene in the presence of base) and a catalytic activator such as dimethylanilinium tetrakis (pentafluorophenyl) borate, and methods for making the same.

Abstract: The present invention is a halogenated support, supported activator and supported transition metal catalyst system involving reacting a carrier containing reactive functionalities with a halogenated organic in the presence of base and contacting a catalytic activator of the formula [C+]−1[M1(Q1−Qn+1)] and/or MnQn a transition metal catalytic precursor with the halogenated support.

Abstract: The present invention is a halogenated support, supported activator and supported transition metal catalyst system involving reacting a carrier containing reactive functionalities with a halogenated organic in the presence of base and contacting a catalytic activator of the formula [C+]−[Mn(Q1-Qn+1)] and/or MnQn a transition metal catalytic precursor with the halogenated support.

Abstract: A cushion element for use in the wheelchair. The cushion element includes a generally rectangular body in plane having a front edge, a pair of opposed side edges and a rear edge. The cushion element is sized and shaped to be placed on a seat support of a wheelchair. The cushion element includes at least one collapsible support located toward the front edge of the element. The collapsible support is characterized by being more easily compressed towards the front edge and less easily compressed towards the rear edge. Thereby, under compression, the collapsible support forms a wedge shaped section in cross-section beneath a wheelchair occupant's legs. In this manner, the person is permitted to reach their foot down to the ground without the formation of a pressure point at the front edge of the seat cushion.

Abstract: A supported polyolefin catalyst activator, comprising a four coordinate anion having a direct chemical bond to a catalyst carrier, wherein said anion is comprised of a neutral, three coordinate compound, MR.sub.3, and a carrier having oxygen containing functionalities, wherein M is selected from the group comprising boron, tellurium, aluminum, gallium, indium and mixtures thereof, and R's can be the same or different and are selected from the group comprising alkyls, alkoxys, alkenyls, halogen substituted alkyls, alkoxys, and alkenyls, aryls, aryl halides, halides and mixtures thereof; and a cation counter ion to said anion, wherein said cation is a protonated base or a Lewis Acid capable of protonating or abstracting a moiety, such as an alkyl or aryl, from a transition metal containing catalyst precursor resulting in a cationic transition metal species.

Abstract: The present invention relates to catalyst supports and improvements thereof for use with supported activators and supported transition metal catalyst systems. The invention specifically involves reacting a carrier containing reactive functionalities, e.g., hydroxyl containing silica, with halogenated organic compounds, e.g., fluorosubstituted phenols. The reaction is preferably carried out in the presence of a base. The reaction consumes undesired functionalities on the support to provide a halogenated support which is suitable for activators and catalytic precursors which are adversely affected by functionalities typically found on supports. The supported activators or catalytic precursors are prepared by contacting the precursors or activators with the halogenated support.