Abstract: The present invention describes a bioinformatic method that can be used in the estimation of an individual's susceptibility to cancer through an evaluation of that individual's personal genome sequence. More specifically, this invention is a continuation-in-part of the methodology described in patent application Ser. No. 14/154,303 for the early detection of cancer. Said method is based upon an analysis of the structure of the repetitive DNA sequences surrounding and within the various cancer-linked regions of the individual's genome being evaluated. Said analysis of said individual's genome is then compared to the same analysis conducted for one or more reference genomes and/or genes for which cancer susceptibility has been previously determined. Said analysis can also be used to estimate the respective likelihoods that each cancer-linked genomic region will be damaged in the potential formation of a tumor.

Abstract: The present invention relates generally to the field of human genetics. More specifically, this invention relates to the clinical application of a bioinformatics methodology described in patent application Ser. No. 14/154,303 for the early detection of cancer. Said clinical application relates to obtaining the genome sequence from an individual's healthy tissue and comparing it to the DNA sequence obtained from that same individual's body tissues, wastes and/or fluids. Said method inspects the DNA sequence obtained from body tissues, wastes and/or fluids for the presence of DNA damage at bioinformatically predicted genetically unstable loci within cancer-linked regions of the patients healthy DNA. The identification of DNA damage within a predicted locus is considered to be evidence of cancer. Said method then uses the unique signature of any damaged DNA sequence which has occurred at predicted unstable cancer-linked loci to construct patient-specific cancer biomarker(s).

Abstract: Methods are provided for regenerating catalyst compositions useful in processes for converting methane to useful hydrocarbons. The methods comprise applying voltage across the catalyst compositions.

Abstract: Methods are provided for converting methane to useful hydrocarbons. In the methods provided, a fluid comprising methane and hydrogen is combined with a catalyst composition derived from at least an aluminum compound, such as an aluminum halide, an aluminum alkyl, or a aluminum hydrate, and a second component such as a transition metal halide, a transition metal hydride, or a zero-valent metal, to produce heavier hydrocarbons.