Abstract: A system and methodology provide for annotating videos with entities and associated probabilities of existence of the entities within video frames. A computer-implemented method identifies an entity from a plurality of entities identifying characteristics of video items. The computer-implemented method selects a set of features correlated with the entity based on a value of a feature of a plurality of features, determines a classifier for the entity using the set of features, and determines an aggregation calibration function for the entity based on the set of features. The computer-implemented method selects a video frame from a video item, where the video frame having associated features, and determines a probability of existence of the entity based on the associated features using the classifier and the aggregation calibration function.

Abstract: A method of modulating some or all copies of a gene in a cell is provided including introducing into a cell one or more ribonucleic acid (RNA) sequences that comprise a portion that is complementary to all or a portion of each of the one or more target nucleic acid sequences, and a nucleic acid sequence that encodes a Cas protein and maintaining the cells under conditions in which the Cas protein is expressed and the Cas protein binds and modulates the one or more target nucleic acid sequences in the cell.

Abstract: Systems and methods for inserting a single pore into a membrane are described herein. A stepped or ramped voltage waveform can be applied across the membranes of the cells of an array, where the voltage waveform starts at first voltage and increases in magnitude over a period of time to a second voltage. The first voltage is selected to be low enough to reduce the risk of damaging the membrane, while the rate of voltage increase is selected to provide sufficient time for the pores to insert into the membranes. Once a pore is inserted into the membrane, the voltage across the membrane rapidly drops, thereby reducing the risk of damaging the membrane even if the applied voltage between the electrodes is further increased.

Abstract: Methods, systems, and devices for wireless communications are described. An access point (AP) may transmit, to a second AP and during a first portion of a transmission opportunity (TxOP), a request to participate in a multi-user (MU) transmission. The AP may receive, from the second AP and during the first portion of the TxOP, an indication of intent to participate in the MU transmission during the second portion of the TxOP, the indication of intent including a resource request of the second AP for participation in the MU transmission. The AP may transmit, during an initial period of the second portion of the TxOP, a trigger signal to the second AP indicating a set of one or more resources for the second AP during the MU transmission. The AP may participate, in conjunction with the second AP and during the second portion of the TxOP, in the MU transmission.

Abstract: A menstrual device having a storage volume. The menstrual device has a frame and a fluid barrier seal layer attached to the exterior surface of the frame. The menstrual device has an expanded configuration that includes an at rest configuration and a deployed configuration. The menstrual device has a compact configuration where the menstrual device is confined to a size, shape and/or geometry smaller than an expanded configuration such that it can be more easily inserted into the body. The menstrual device in a compact configuration is contained within an applicator, where the applicator assists in ejecting the menstrual device into the body.

Abstract: A method for detecting cells having granules expressing G protein coupled receptor-associated sorting protein 1 (GASP-1) or a fragment thereof is provided. The detection method may comprise: (a) contacting the cells with an effective amount of a binding protein, wherein the binding protein comprises an antigen binding fragment that specifically binds GASP-1; and (b) identifying cells having granules bound to the binding protein. The GASP-1 granules may be in the cytosol or on the surface of the cells. Also provided are methods for producing T-cells comprising a chimeric antigen receptor, anti-GASP-1 antibody or a bi-specific binding protein. Further provided are methods for treating GASP-1-mediated to disease or inactivating exosomes, microvesicles or oncosomes.

Abstract: Embodiments of the present disclosure relate to a method, system, and computer program product for efficient execution of a decision tree. According to the method, respective target values of a plurality of attributes of a target entity are obtained. Representations of a plurality of leaf nodes of a decision tree are obtained. Each of the representations indicates respective statistic values of a plurality of attributes of historical entities and a statistic prediction result determined from historical prediction results output at a respective one of the plurality of leaf nodes for the historical entities. Distance measures between the target entity and the plurality of leaf nodes are determined based on the target values and the statistic values indicated by the representations of the plurality of leaf nodes. A target prediction result for the target entity is determined based on the distance measures and the statistic prediction results of the historical entities.

Abstract: Described herein are manufacturing techniques for achieving stress isolation in microelectromechanical systems (MEMS) devices that involve isolation trenches formed from the backside of the substrate. The techniques described herein involve etching a trench in the bottom side of the substrate subsequent to forming a MEMS platform, and processing the MEMS platform to form a MEMS device on the top side of the substrate subsequent to etching the trench.

Abstract: A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner.

Abstract: The present disclosure relates to multispecific molecules comprising a peptide-MHC complex and an immune cell antigen targeting moiety. Particular aspects relate to multimeric (e.g., dimeric) molecules comprising a peptide-MHC complex, an immune cell antigen targeting moiety, and a multimerization moiety. The disclosure further provides pharmaceutical compositions comprising the multispecific molecules, and methods of use of multispecific molecules in antigen-specific T cell activation, in inducing an antigen-specific immune response, and in therapeutic applications, as well as nucleic acids encoding the multispecific molecules, recombinant cells that express the multispecific molecules, and methods of producing the multispecific molecules.

Abstract: A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner.

Abstract: The disclosed technology is generally directed to downlink prioritization of on-orbit spaceborne data. In one example of the technology, image metadata and raw image data obtained from sensors on the constrained-environment device are stored. The raw image data includes a plurality of images. A plurality of images tiles is provided such that the plurality of images tiles includes, for each image of the plurality of images, evenly-spaced portions of the image. Via an embedding-generation model, a plurality of embeddings is generated based on the plurality of image tiles. The plurality of embeddings is used to perform a prioritization of image tiles among the plurality of image tiles. During a downlink session from the constrained-environment device, image tiles from among the plurality of image tiles are downlinked based, at least in part, on the prioritization.

Abstract: A method for detecting and tracking tainted cryptographic wallets. The method measures a wallet's propensity to engage in criminal or suspicious activity. Naturally, transacting with a criminal is tantamount either to funding crime or laundering its proceeds, so it is in our collective interest to identify—and then monitor or quarantine—any wallet with criminal association. The method also automatically flags risky withdrawal requests in real-time for further review before committing them to the blockchain. In some embodiments, the exchange can quarantine wallets at a certain Walletscore.

Abstract: Methods, systems, and devices for wireless communications are described. A first wireless device (e.g., station (STA), access point (AP)) may transmit to a second wireless device during a service period, an initiating frame using a transmit beam that is based on a first beam training procedure performed between the devices prior to the service period. The first wireless device may perform a second beam training procedure during the service period based on an absence of a response frame from the second wireless device, based on an indication within the response frame received from the second wireless device, or based on identification of a change in a wireless channel relative to a previous beam training interval or previous service period. The first wireless device may then communicate one or more messages with the second wireless device using one or more beams that are based on the second beam training procedure.

Abstract: A method includes receiving, as input, reference audio data representing a reference audio signal captured by an audio input device. The method also includes receiving, as input, from a beamformer, spatially-filtered audio data representing an output of the beamformer, the beamformer configured to spatially filter, based on additional audio data captured by one or more additional audio input devices, the reference audio data to attenuate one or more interfering signals in the spatially-filtered audio data. The method processes, using a trained guided speech-enhancement network, the reference audio data and the spatially-filtered audio data to generate, as output, enhanced audio data, the guided speech-enhancement network processing the reference audio data and the spatially-filtered audio data to further attenuate, in the enhanced audio data, the one or more interfering signals attenuated by the beamformer.

Abstract: Inferential analysis includes: assessing risk of a cyber security failure in a computer network of an entity, using a computer agent configured to collect information from at least one accessible Internet elements, automatically determining, based on the assessed risk, a change or a setting to at least one element of policy criteria of a cyber security policy; and automatically recommending, based on the assessed risk, a computer network change to reduce the assessed risk.

Abstract: Herein disclosed is a material comprising: a premixed paste, comprising: one or more barium cements that are capable of a hydration reaction with water to form a hydrogel; and a nonaqueous liquid carrier that is hydrophilic and able to undergo an exchange with a water-based liquid when the premixed paste is exposed to an environment where water-based liquids are present. Uses of the herein disclosed material are also disclosed.

Abstract: A space conditioning system and method for monitoring electrical parameters and/or thermodynamic parameters relating to the heat of extraction/rejection or power consumption of the system and to communicate the monitored parameters to an external device.

Abstract: A space conditioning system and method for monitoring electrical parameters and/or thermodynamic parameters relating to the heat of extraction/rejection or power consumption of the system and to communicate the monitored parameters to an external device.

Abstract: Method, systems, and apparatus for identifying engagement data representing user interest in renting or purchasing a property, wherein the engagement data comprises impression data, tenant application data, messaging data, appointment data, or rental data; calculating, using a machine-learning model, a price adjustment for the property based on at least the engagement data; and adjusting a price for the property based on the price adjustment