Patents by Inventor George Yousef

George Yousef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel kallikrein gene
    Publication number: 20070178114
    Abstract: The invention relates to nucleic acid molecules, proteins encoded by such nucleic acid molecules; and use of the proteins and nucleic acid molecule.
    Type: Application
    Filed: March 29, 2007
    Publication date: August 2, 2007
    Applicant: Mount Sinai Hospital
    Inventors: George Yousef, Eleftherios Diamandis
  • Methods for detecting endocrine cancer
    Publication number: 20060223059
    Abstract: Kallikrein 12, kallikrein 14, and kallikrein 15 proteins, and nucleic acids encoding the proteins have particular application in the detection of endocrine cancer, in particular ovarian cancer. Kallikrein 12, kallikrein 14, and kallikrein 15 proteins and nucleic acid molecules encoding the proteins constitute new biomarkers for diagnosis and monitoring (i.e. monitoring progression or therapeutic treatment) of endocrine cancer.
    Type: Application
    Filed: September 26, 2003
    Publication date: October 5, 2006
    Applicant: Mount Sinai Hospital
    Inventors: George Yousef, Eleftherios Diamandis
  • Methods for detecting endocrine cancer
    Publication number: 20060159616
    Abstract: Kallikrein 13 constitutes a novel biomarker for diagnosis, treatment and monitoring of endocrine cancer. A method is provided for diagnosing and monitoring endocrine cancer or a predisposition to endocrine cancer, in a subject comprising detecting hK13 in a sample from the subject. Imaging methods, screening methods for test agents for inhibiting breast or ovarian cancer, and therapeutic applications based on kallikrein 13 are also described.
    Type: Application
    Filed: August 28, 2003
    Publication date: July 20, 2006
    Applicant: Mount Sinai Hospital
    Inventors: George Yousef, Elefttherious Diamandis
  • Novel human kallikrein-like genes
    Publication number: 20060134114
    Abstract: The invention relates to nucleic acid molecules, kallikrein-like proteins encoded by such nucleic acid molecules; and use of the proteins and nucleic acid molecules.
    Type: Application
    Filed: December 28, 2005
    Publication date: June 22, 2006
    Applicant: Mt. Sinai Hospital
    Inventors: George Yousef, Eleftherios Diamandis
  • Methods for detecting breast and ovarian cancer
    Publication number: 20060073525
    Abstract: Kallikrein 5 constitutes a novel biomarker for diagnosis, treatment and monitoring of breast and ovarian cancer. A method is provided for diagnosing and monitoring breast or ovarian cancer or a predisposition to breast or ovarian cancer, in a subject comprising detecting kallikrein 5 in a sample from the subject. Imaging methods, screening methods for test agents for inhibiting breast or ovarian cancer, and therapeutic applications based on kallikrein 5 are also described.
    Type: Application
    Filed: August 28, 2003
    Publication date: April 6, 2006
    Applicant: Mount Sinai Hospital
    Inventors: George Yousef, Eleftherios Diamandis
  • Methods for detecting ovarian cancer
    Publication number: 20050176002
    Abstract: Methods for diagnosing and monitoring ovarian carcinoma in a subject are described comprising measuring KLK9 or hK9 in a sample from the subject. The invention also provides localization or imaging methods for ovarian cancer, and kits for carrying out the methods of the invention. The invention also contemplates therapeutic applications for ovarian cancer employing hK9 proteins, nucleic acid and molecules encoding the proteins, and/or binding agents for the proteins.
    Type: Application
    Filed: October 16, 2002
    Publication date: August 11, 2005
    Applicant: MOUNT SINAI HOSPITAL
    Inventors: Eleftherios Diamandis, George Yousef