Patents by Inventor George Z. Zhu

George Z. Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liposome composition and method for administration of a radiosensitizer
    Patent number: 6818227
    Abstract: A method for administering a radiosensitizer to a tumor site in a subject is described. The method includes preparing liposomes composed of a vesicle-forming lipid and a lipid-derivatized radiosensitizer. In one embodiment, the radiosensitizer is dipalmitoyl-5-iodo-2′-deoxyuridine. A method for preparing the liposome composition including the lipid-derivatized radiosensitizer is also disclosed.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: November 16, 2004
    Assignee: Alza Corporation
    Inventors: Paul S. Uster, Adam A. Zetter, Kristen M. Hjortsvang, James L. Slater, George Z. Zhu
  • Liposome loading method using a boronic acid compound
    Patent number: 6051251
    Abstract: A method for loading a therapeutic compound having a cis diol moiety into pre-formed liposomes is described. The method includes adding to a suspension of liposomes (i) the compound to be loaded into the liposomes and (ii) a boronic acid compound, thereby achieving accumulation of the compound within the liposomes.
    Type: Grant
    Filed: November 19, 1998
    Date of Patent: April 18, 2000
    Assignee: Alza Corporation
    Inventors: Samuel Zalipsky, Paul S. Uster, George Z. Zhu