Patents by Inventor Georges Boffa

Georges Boffa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression in non-tumoral human lymphoblastoid lines with an integrative vector
    Patent number: 5789247
    Abstract: A plasmid vector designed for transforming lymphoblastoid cells, immortalized by Epstein Barr virus, for producing heterologous proteins, which comprises the bacterial DNA elements required for its amplification together with the following DNA fragments:the DNA elements which constitute an expression cassette allowing the insertion of a heterologous DNA to be expressed in the human lymphoblastoid cells,the Adenovirus 5 derived DNA sequence encoding the VA I and VA II RNA aimed at optimizing the messenger RNA translation,a gene engineered to be efficient as a selective marker in eukaryotic cells, andDNA segments selected for their property to promote plasmid DNA integration into the cell chromosome DNA.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: August 4, 1998
    Inventors: Annick Ballay, Georges Boffa, Jean-Pierre Cartron, Stany Chretien, Patrick Lambin, Claude Lopez, Sylvie Prigent, Charles Salmon