Abstract: An electrical cable assembly amenable to implantation into a body includes a flexible cable. The flexible cable includes a dielectric substrate, a conductor lead for conducting an electrical signal, a conductive barrier layer, and an overmold layer. The conductor lead is embedded within and surrounded by the dielectric substrate. The conductive barrier layer surrounds the dielectric substrate and encases the dielectric substrate and conductor lead in a cavity. The conductive barrier layer is a continuous material layer that is neither braided nor spiral wrapped and provides a hermetic barrier formed of a metallic or inorganic material. The overmold layer provides one or more of mechanical protection or strain relief to the conductive barrier layer.