Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.

Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynecological condition in which an activity of AR and/or ER is a contributory factor in a subject.

Abstract: History for data objects may be maintained to detect data events. An indication of an Extract, Transform, Load (ETL) process applied to one or more source data objects to generate one or more transformed data objects may be received. History for the source data objects may be updated to include the transformed data objects and the ETL process that generated the transformed data objects. An evaluation of the update may be performed to determine whether an event associated with the data lineage is triggered. If the event is triggered, a notification of the event may be sent to one or more subscribers for the event.

Abstract: Recognizing unknown data objects may be implemented for data objects stored in a data store. Data objects that are identified as unknown may be accessed to retrieve a portion of the data object. Different representations of the data object may be generated for recognizing different data schemas. An analysis of the representations may be performed to identify a data schema for the unknown data object. The data schema may be stored in a metadata store for the unknown data object.

Abstract: Extract, Transform, Load (ETL) processing may be initiated by detected events. A trigger event may be associated with an ETL process apply one or more transformations to a source data object. The trigger event may be detected for the ETL process and evaluated with respect to one or more execution conditions for the ETL process. If the execution conditions for the ETL process are satisfied, then the ETL process may be executed. At least some of the source data object may be obtained, the one or more transformations of the ETL process may be applied, and one or more transformed data objects may be stored.

Abstract: Data transformation workflows may be generated to transform data objects. A source data schema for a data object and a target data format or target data schema for a data object may be identified. A comparison of the source data schema and the target data format or schema may be made to determine what transformations can be performed to transform the data object into the target data format or schema. Code to execute the transformation operations may then be generated. The code may be stored for subsequent modification or execution.

Abstract: A system adapted to process long-running processes is disclosed. A request to upload data is received at a server. The server divides the data into multiple parts and launches a separate process to upload each of the divided parts. The server records for each process the processing time or duration that the particular process used to upload its corresponding data item. The server maintains an average processing duration that is calculated from the processing durations of the completed processes. The server identifies that one process is continuing to run and compares a processing duration for the particular process to a threshold derived from the average processing duration. If the processing duration for the particular process exceeds the threshold, the server initiates a new process to upload the same data item. When one of either the new process or the still running process has completed processing, the server terminates the other process.

Abstract: Disclosed is selective removal of mercury from aqueous feeds also including precious metals. In particular, the present invention is useful for removal of mercury from processing waters produced during precious metal mining processes. The process includes contacting the aqueous feed solution with a solid sorbent material including thiol and/or thiolate functional groups, wherein (i) the aqueous feed solution includes at least 10 ppm of free cyanide ions; and/or (ii) the sorbent material is contacted with an aqueous cyanide solution after contact with the aqueous feed solution to selectively desorb precious metal from the sorbent material.

Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].

Abstract: The invention features diagnostic and therapeutic methods and compositions featuring androgen receptor variant proteins and nucleic acid molecules whose expression is increased in androgen related diseases or disorders.

Abstract: A system for optically recognizing, interpreting, and digitizing human readable instruments, annunciators, and controls includes an image acquisition sensor operable to capture images of at least one of the instruments, annunciators, and controls; and a logic processing unit operable to decode the images captured by the image acquisition sensor and interpret the decoded images to determine a state of the at least one of the instruments, annunciators, and controls.

Abstract: A system for obtaining substantially all medical information available to a specific patient from satellite portals and adapted to report that information to authorized individuals and satellite portals. The system polls the satellite portals for the medical information and interfaces with the satellite portals without requiring the patient to interface with the API that intervenes upon patient query between the satellite portal and the patient.

Abstract: A motion capture environment includes at least one sensor-tracker for tracking a location of a tracked object within the motion capture environment and one or more computers collectively operable to generate a virtual reality environment including a virtual control panel having a virtual control that, when actuated, effects a predetermined result in the virtual reality environment; determine a virtual location of the tracked object within the virtual reality environment; and determine when the virtual location of the tracked object coincides with the location of the virtual control to actuate the virtual control. The motion capture environment further includes a display device for displaying the virtual reality environment to an actor within the motion capture environment.

Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.

Abstract: Provided is a septal splint to promote healing and alignment of a user's septum, and a method thereof. The septal splint includes an alignment member including a plurality of bilateral support pads to contact left and right sides of the user's septum, and a plurality of medializing support floor pads to rest on a bottom portion of each of the user's nasal passages. The septal splint also includes a pressing member, including a plurality of pressure applicators to transfer a predetermined amount of pressure to the bilateral support pads such that an alignment of the user's septum, maxillary crest, and fibrous tissue therebetween, is maintained, and a fulcrum end to supply the predetermined pressure to the plurality of pressure applicators. The septal splint promotes healing and alignment of a user's septum by providing moderate pressure at a junction point of the patient's maxillary crest, septum base, and fibrous tissue therebetween.

Abstract: A method, software and system allows for the novel and seamless integration between disparate hardware and software systems to facilitate strong authentication and identity assertion of an individual as an integral component of transaction processing. The method, software and system can combine quick response (QR) code(s) with more custom mobile device uniform resource locator (URL) scheme(s) to seamlessly invoke mobile application(s) that enable an end user to perform strong, multi-factor authentication as a component of completing a transaction. The use of mobile application(s) can simplify and automate the conveyance of transaction details between computing platforms and devices to allow a user to fully participate in a transaction approval process with a simplified, convenient experience.

Abstract: Actuators are attached with plates of a fuel cell stack. Electrical power is provided to the actuators to drive the actuators to mechanically excite the plates to agitate liquid water restricting or blocking flow fields formed in the plates.

Abstract: An air management system that allows safe and convenient forms of interval training exercise to be performed on pneumatically elevating rebound exercise equipment. The system includes at least one air intake valve and bleed valve. By providing repeatable degrees of difficulty for both air intake and air release from the extendable air springs employed for the exercise, competitive athletes and their coaches can design, employ, repeat, and compare individualized medium- or high-intensity interval protocols for optimal cardiovascular training programs.

Abstract: Methods are disclosed for preparing lignin from lignocellulosic biomass using rapid full or partial pressure reduction to separate and pulverize the lignin without fouling the equipment and with improved energy recovery.

Abstract: A method, software and system allows for the novel and seamless integration between disparate hardware and software systems to facilitate strong authentication and identity assertion of an individual as an integral component of transaction processing. The method, software and system can combine quick response (QR) code(s) with more custom mobile device uniform resource locator (URL) scheme(s) to seamlessly invoke mobile application(s) that enable an end user to perform strong, multi-factor authentication as a component of completing a transaction. The use of mobile application(s) can simplify and automate the conveyance of transaction details between computing platforms and devices to allow a user to fully participate in a transaction approval process with a simplified, convenient experience.