Abstract: Methods and systems are provided for a proactive approach for computer forensic investigations. The invention allows organizations anticipating the need for forensic analysis to prepare in advance. Forensic signatures are created including a digital fingerprint and other information associated with a file. In one aspect, informational signatures are created, which may assist in determining what information is included in a file. In another aspect, the digital fingerprint may represent contents of the file and is resistant to minor modification of the file. In another aspect, fingerprints can be compared in parallel on different computers.

Abstract: Disclosed are compositions and methods related to assessing the risk of cancer, such as breast cancer and lung cancer, through analyzing the length of telomeres, such as chromosome 9p, 15p, and/or Xp telomere, such as the short arm of the 9p, 15p, and/or Xp telomere. For example, if the 9p, 15p, and/or Xp arm is shorter than normal, the risk of cancer is increased.

Abstract: The invention is directed towards methods of treating abnormal tissues in a subject or sensitizing an abnormal tissue to a chemotherapeutic agent. The methods comprise screening at least a portion of an abnormal tissue for at least one mutant form of p53 protein, and administering at least one isothiocyanate (ITC) to the subject or abnormal tissue if the abnormal tissue is positive for the at least one mutant form of p53.