Patents by Inventor Georgia Giannoukos

Georgia Giannoukos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and systems for analyzing guide RNA molecules
    Patent number: 11499151
    Abstract: The present disclosure relates to methods of assessing a sample of guide RNAs (gRNAs).
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: November 15, 2022
    Assignee: Editas Medicine, Inc.
    Inventors: Cecilia Fernandez, Georgia Giannoukos, Luis Barrera, Dawn Ciulla, Terence Ta
  • HiC: Method Of Identifying Regulatory Interactions Between Genomic Loci
    Publication number: 20210040547
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Application
    Filed: August 11, 2020
    Publication date: February 11, 2021
    Inventors: Job Dekker, Erez Lieberman Aiden, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos
  • HiC: method of identifying interactions between genomic loci
    Patent number: 10745744
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: August 18, 2020
    Assignees: University of Massachusetts, Massachusetts Institute of Technology, President and Fellows of Harvard College, Whitehead Institute for Biomedical Research
    Inventors: Job Dekker, Erez Lieberman Aiden, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos
  • METHODS OF ASSESSING NUCLEASE CLEAVAGE
    Publication number: 20200232022
    Abstract: The present disclosure relates to methods of analyzing activity of nucleases, such as ZFNs, TALENs or CRISPR-associated nucleases, in particular their cutting at “off-target” loci.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 23, 2020
    Inventors: Georgia Giannoukos, Christopher Wilson, Dawn Ciulla
  • METHODS AND SYSTEMS FOR ANALYZING GUIDE RNA MOLECULES
    Publication number: 20200190513
    Abstract: The present disclosure relates to methods of assessing a sample of guide RNAs (gRNAs).
    Type: Application
    Filed: April 27, 2018
    Publication date: June 18, 2020
    Applicant: Editas Medicine, Inc.
    Inventors: Cecilia FERNANDEZ, Georgia GIANNOUKOS, Luis BARRERA, Dawn CIULLA, Terence TA
  • HiC: Method of Identifying Interactions Between Genomic Loci
    Publication number: 20170369937
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Application
    Filed: June 15, 2017
    Publication date: December 28, 2017
    Inventors: Job Dekker, Erez Lieberman Aiden, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos
  • HiC: method of identifying interactions between genomic loci
    Patent number: 9708648
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: July 18, 2017
    Assignees: University of Massachusetts, Massachusetts Institute of Technology, President and Fellows of Harvard College, Whitehead Institute for Biomedical Research
    Inventors: Job Dekker, Erez Lieberman Aiden, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos
  • HiC: Method of Identifying Interactions Between Genomic Loci
    Publication number: 20160312273
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Application
    Filed: April 25, 2016
    Publication date: October 27, 2016
    Inventors: Job Dekker, Erez Lieberman Aiden, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos
  • Methods of identifying interactions between genomic loci
    Patent number: 9434985
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: September 6, 2016
    Assignees: University of Massachusetts, Massachusetts Institute Of Technology, President And Fellows Of Harvard College, Whitehead Institute For Biomedical Research
    Inventors: Job Dekker, Erez Lieberman, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos
  • METHODS OF IDENTIFYING INTERACTIONS BETWEEN GENOMIC LOCI
    Publication number: 20130096009
    Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
    Type: Application
    Filed: September 22, 2009
    Publication date: April 18, 2013
    Applicants: University of Massachusetts, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Job Dekker, Erez Lieberman, Nynke Van Berkum, Andreas Gnirke, Eric Lander, Chad Nusbaum, Louise Williams, Alexandre Melnikov, Georgia Giannoukos