Patents by Inventor Georgiann B. Melink

Georgiann B. Melink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunotherapy protocol of culturing leukocytes in the presence of interleukin-2 in a hollow fiber cartridge
    Patent number: 5631006
    Abstract: An immunotherapy protocol in which leukocytes are cultured in the presence of interleukin-2 in a hollow fiber cartridge perfusion system for at least four days to achieve a harvest yield of at least 100% of leukocytes with respect to the number of cells initially present in the hollow cartridge, and where the leukocytes have a lytic activity at least equal to that of cells grown in a static culturing system and where the lytic activity of the cells following the culture period in the hollow fiber is at least equal to cells grown in a static culturing system.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 20, 1997
    Assignee: Endotronics, Inc.
    Inventors: Georgiann B. Melink, Raji A. Shankar
  • Method of culturing leukocytes
    Patent number: 5541105
    Abstract: A method for culturing leukocytes includes the culturing of leukocytes in a hollow fiber cartridge perfusion system for at least four days to achieve a harvest yield of at least 100% of leukocytes, the leukocytes having a lytic activity at least equal to that of cells grown in a static culturing system.
    Type: Grant
    Filed: April 26, 1994
    Date of Patent: July 30, 1996
    Assignee: Endotronics, Inc.
    Inventors: Georgiann B. Melink, Raji A. Shankar