Patents by Inventor Georgios Samonis

Georgios Samonis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical formulations: liposomes incorporating aromatic polyene antibiotics
    Patent number: 4999199
    Abstract: The present invention involves a pharmaceutical formulation comprising a liposome having a therapeutically effective concentration of an aromatic polyene macrolide antibiotic. The aromatic polyene macrolide antibiotic usable in the practice of the present invention is selected from the group consisting of candicidin, hamycin, aurefungin, ascosin, ayfattin, azacolutin, DJ400-B, trichomycin, levorin, heptamycin, candimycin or perimycin. The most preferred aromatic polyene macrolide antibiotic is candicidin. An important aspect of the present invention is a method for treating disseminated fungal infection in an animal comprising administering to an animal such as a human a pharmaceutical formulation comprising a liposome having a therapeutically effective amount of aromatic polyene macrolide antibiotic as described above.
    Type: Grant
    Filed: November 10, 1988
    Date of Patent: March 12, 1991
    Assignee: Board of Regents, The University of Texas System
    Inventors: Elias J. Anaissie, Georgios Samonis, Hans Krause, Gerald P. Bodey