Patents by Inventor Georgios Trichonas

Georgios Trichonas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10639345
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: May 5, 2020
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Demetrios G. Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami
  • Publication number: 20190216881
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: October 26, 2018
    Publication date: July 18, 2019
    Inventors: Demetrios G. Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami
  • Patent number: 10149884
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: December 11, 2018
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Demetrios Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami
  • Publication number: 20170216393
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: October 7, 2016
    Publication date: August 3, 2017
    Inventors: Demetrios Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami
  • Patent number: 9492432
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: November 15, 2016
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Demetrios Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami
  • Publication number: 20160250189
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: November 6, 2015
    Publication date: September 1, 2016
    Inventors: Demetrios Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami
  • Publication number: 20130137642
    Abstract: Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
    Type: Application
    Filed: April 23, 2011
    Publication date: May 30, 2013
    Inventors: Demetrios Vavvas, Georgios Trichonas, Joan W. Miller, Yusuke Murakami