Patents by Inventor Gerald A. Soff

Gerald A. Soff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer blood test using BC200 RNA isolated from peripheral blood for diagnosis and treatment of invasive breast cancer
    Patent number: 9777334
    Abstract: Compositions and methods for diagnosing an increased risk for the development of aggressive, invasive breast cancer are provided.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: October 3, 2017
    Assignee: The Research Foundation for State University of New York
    Inventors: Henri Tiedge, Anna Iacoangeli, Gerald A. Soff
  • Cancer Blood Test Using BC200 RNA Isolated from Peripheral Blood for Diagnosis and Treatment of Invasive Breast Cancer
    Publication number: 20150087538
    Abstract: Compositions and methods for diagnosing an increased risk for the development of aggressive, invasive breast cancer are provided.
    Type: Application
    Filed: March 14, 2013
    Publication date: March 26, 2015
    Inventors: Henri Tiedge, Anna Iacoangeli, Gerald A. Soff
  • Cyclic peptide antitumor agents
    Patent number: 8492345
    Abstract: Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: July 23, 2013
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Shouxin Liu, Wenxin Gu, Thomas E. Adrian, Gerald A. Soff
  • CYCLIC PEPTIDE ANTITUMOR AGENTS
    Publication number: 20120122799
    Abstract: Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
    Type: Application
    Filed: November 14, 2011
    Publication date: May 17, 2012
    Applicant: Northwestern University
    Inventors: Richard B. Silverman, Shouxin Liu, Wenxin Gu, Thomas E. Adrian, Gerald A. Soff
  • Cyclic peptide antitumor agents
    Patent number: 8058244
    Abstract: Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: November 15, 2011
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Shouxin Liu, Wenxin Gu, Thomas E. Adrian, Gerald A. Soff
  • Cyclic Peptide Antitumor Agents
    Publication number: 20100204088
    Abstract: Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
    Type: Application
    Filed: March 11, 2010
    Publication date: August 12, 2010
    Inventors: Richard B. Silverman, Shouxin Liu, Wenxin Gu, Thomas E. Adrian, Gerald A. Soff
  • Cyclic peptide antitumor agents
    Patent number: 7709443
    Abstract: Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: May 4, 2010
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Shouxin Liu, Wenxin Gu, Thomas E. Adrian, Gerald A. Soff
  • Methods and compositions for generating angiostatin
    Publication number: 20060099671
    Abstract: The invention provides methods of generating angiostatin in vitro comprising contacting plasminogen with a plasminogen activator and a sulfhydryl donor or contacting plasmin with a sulfhydryl donor. The invention also provides a method of treating angiogenic diseases by administering to an animal suffering from such a disease a sulfhydryl donor, a plasminogen activator, or a combination of a sulfhydryl donor and a plasminogen activator. The invention further comprises a composition for generating angiostatin comprising a sulfhydryl donor and a plasminogen activator. The invention also provides a container holding a sulfhydryl donor and/or a plasminogen activator, said container having a label thereon instructing administration of the sulfhydryl donor and/or plasminogen activator to an animal suffering from an angiogenic disease.
    Type: Application
    Filed: December 22, 2005
    Publication date: May 11, 2006
    Inventors: Gerald Soff, Stephen Gately, Przemyslaw Twardowski
  • Cyclic peptide antitumor agents
    Publication number: 20050159346
    Abstract: Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
    Type: Application
    Filed: October 8, 2004
    Publication date: July 21, 2005
    Inventors: Richard Silverman, Shouxin Liu, Wenxin Gu, Thomas Adrian, Gerald Soff
  • Methods and compositions for generating angiostatin
    Patent number: 6576609
    Abstract: The invention provides a method of treating a neoplastic disease in a human by administering a therapeutically effective amount of plasminogen activator effective to increase the amount of angiostatin present in the human to treat the disease. The invention also provides a method of treating a neoplastic disease in a human by administering a therapeutically effective amount of plasminogen activator and sulfhydryl donor effective to increase the amount of angiostatin present in the human to treat said disease.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: June 10, 2003
    Assignee: Northwestern University
    Inventors: Gerald Soff, Stephen T. Gately, Przemyslaw Twardowski
  • Methods and compositions for generating angiostatin
    Patent number: 5801012
    Abstract: The invention provides a method of generating angiostatin in vitro comprising contacting plasminogen or plasmin with a plasminogen activator and a sulfhydryl donor.
    Type: Grant
    Filed: September 17, 1996
    Date of Patent: September 1, 1998
    Assignee: Northwestern University
    Inventors: Gerald Soff, Stephen T. Gately, Przemyslaw Twardowski