Patents by Inventor Gerald Alexander
Gerald Alexander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11913016Abstract: Methods of making synthetic yeast cells by mating together two diploid (or higher ploidy) yeast species or hybrids to generate multi-ploid yeast hybrids are provided herein. The synthetic yeast cells made by this process and kits for performing the process are also provided.Type: GrantFiled: November 7, 2017Date of Patent: February 27, 2024Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: William Gerald Alexander, David Peris Navarro, Christopher Todd Hittinger
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Patent number: 11730838Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: GrantFiled: February 17, 2021Date of Patent: August 22, 2023Assignee: UNIVERSITY OF STRATHCLYDEInventors: John Galloway Anderson, Michelle Maclean, Gerald Alexander Woolsey, Scott John MacGregor
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Publication number: 20210236670Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: ApplicationFiled: February 17, 2021Publication date: August 5, 2021Inventors: John Galloway Anderson, Michelle Maclean, Gerald Alexander Woolsey, Scott John MacGregor
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Patent number: 10953117Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: GrantFiled: November 8, 2017Date of Patent: March 23, 2021Assignee: University of StrathclydeInventors: John Galloway Anderson, Michelle Maclean, Gerald Alexander Woolsey, Scott John MacGregor
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Patent number: 10870858Abstract: Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.Type: GrantFiled: January 24, 2018Date of Patent: December 22, 2020Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Christopher Todd Hittinger, William Gerald Alexander
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Patent number: 10738630Abstract: A platform apparatus for a propulsion rotor having an annular array of airfoils carried by a rotor disk. The apparatus includes: at least one forward segment comprising an arcuate forward body having a plurality of spaced-apart axially-extending forward fingers, each of the forward fingers bounded by a curved first lateral edge interconnected to a straight second lateral edge by an aft edge, wherein the forward segment defines a flow path surface and an opposed back surface; at least one aft segment comprising an arcuate aft body having a plurality of spaced-apart actually-extending aft fingers, each of the aft fingers bounded by a curved first lateral edge interconnected to a straight second lateral edge by a forward edge, wherein the aft segment defines a flow path surface and an opposed back surface, and wherein the aft edges have a shape complementary to a shape of the forward edges.Type: GrantFiled: February 19, 2018Date of Patent: August 11, 2020Assignee: General Electric CompanyInventors: Qiang Li, Nicholas Joseph Kray, Gerald Alexander Pauley, Ming Xie, Jorge Orlando Lamboy, Tod Winton Davis
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Patent number: 10605117Abstract: A gas turbine including a fan platform positioned between adjacent fan blades of a fan of the gas turbine engine is provided. The fan platform defines an outer surface that at least partially defines an inner flowpath boundary of the fan. Additionally, the fan platform includes at least two components attached to one another. At least one of the components of the fan platform defines an enclosed void. An insert is positioned within the enclosed void formed of a material defining a relatively low Young's modulus. The insert may prevent resin from filling the enclosed void during assembly/manufacture of the fan platform, while also reducing a weight of the fan platform and an amount of stress on the fan platform.Type: GrantFiled: October 8, 2015Date of Patent: March 31, 2020Assignee: General Electric CompanyInventors: Mingchao Wang, Gerald Alexander Pauley
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Publication number: 20190257210Abstract: A platform apparatus for a propulsion rotor having an annular array of airfoils carried by a rotor disk. The apparatus includes: at least one forward segment comprising an arcuate forward body having a plurality of spaced-apart axially-extending forward fingers, each of the forward fingers bounded by a curved first lateral edge interconnected to a straight second lateral edge by an aft edge, wherein the forward segment defines a flow path surface and an opposed back surface; at least one aft segment comprising an arcuate aft body having a plurality of spaced-apart actually-extending aft fingers, each of the aft fingers bounded by a curved first lateral edge interconnected to a straight second lateral edge by a forward edge, wherein the aft segment defines a flow path surface and an opposed back surface, and wherein the aft edges have a shape complementary to a shape of the forward edges.Type: ApplicationFiled: February 19, 2018Publication date: August 22, 2019Inventors: Qiang Li, Nicholas Joseph Kray, Gerald Alexander Pauley, Ming Xie, Jorge Orlando Lamboy, Tod Winton Davis
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Publication number: 20180154027Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: ApplicationFiled: November 8, 2017Publication date: June 7, 2018Inventors: John Galloway Anderson, Michelle Maclean, Gerald Alexander Woolsey, Scott John MacGregor
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Publication number: 20180155732Abstract: Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.Type: ApplicationFiled: January 24, 2018Publication date: June 7, 2018Applicant: Wisconsin Alumni Research FoundationInventors: Christopher Todd Hittinger, William Gerald Alexander
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Patent number: 9879270Abstract: Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.Type: GrantFiled: August 14, 2015Date of Patent: January 30, 2018Assignee: Wisconsin Alumni Research FoundationInventors: Christopher Todd Hittinger, William Gerald Alexander
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Patent number: 9839706Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: GrantFiled: March 13, 2015Date of Patent: December 12, 2017Assignee: University of StrathclydeInventors: John Galloway Anderson, Michelle Maclean, Gerald Alexander Woolsey, Scott John MacGregor
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Publication number: 20170101876Abstract: A gas turbine including a fan platform positioned between adjacent fan blades of a fan of the gas turbine engine is provided. The fan platform defines an outer surface that at least partially defines an inner flowpath boundary of the fan. Additionally, the fan platform includes at least two components attached to one another. At least one of the components of the fan platform defines an enclosed void. An insert is positioned within the enclosed void formed of a material defining a relatively low Young's modulus. The insert may prevent resin from filling the enclosed void during assembly/manufacture of the fan platform, while also reducing a weight of the fan platform and an amount of stress on the fan platform.Type: ApplicationFiled: October 8, 2015Publication date: April 13, 2017Inventors: Mingchao Wang, Gerald Alexander Pauley
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Publication number: 20170101878Abstract: A gas turbine engine including a component having a first and a second component that are attached or integrally formed with each other. The first and the second component define an enclosed void. An insert is positioned within the enclosed void which is formed of a material having a relatively low Young's modulus. The insert may prevent resin from filling the enclosed void during assembly/manufacture of the component, while also reducing a weight of the component and an amount of stress on the component. The component may be a fan platform positioned between a plurality of fan blades, an outlet guide vane, or another component of the gas turbine engine.Type: ApplicationFiled: July 19, 2016Publication date: April 13, 2017Inventors: Mingchao Wang, Gerald Alexander Pauley, Courtney James Tudor, Elzbieta Kryj-Kos, Weizeng Kong
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Patent number: 9399922Abstract: Described are a gas turbine engine fan blade platform, related rotor assembly and gas turbine engine, as well as a method of assembling the same. The platform has a forward portion proximal to an axis of rotation, an aft portion, and a transition portion between the forward and aft portions. The forward portion has a forward interface surface facing axially forward, the aft portion has an aft interface surface facing radially outward, and the transition portion has at least one mounting feature. For the method of assembly, an aft support is installed on a fan disk and booster spool assembly. A plurality of fan blades are installed into a fan disk, followed by installing a fan platform between adjacent blades and securing the mounting features to the disk, thereby filling the annulus of the fan disk. Finally, a forward support is installed on the fan disk.Type: GrantFiled: December 31, 2012Date of Patent: July 26, 2016Assignee: General Electric CompanyInventors: Jorge Orlando Lamboy, Matthew Glen Gann, Nicholas Joseph Kray, Gerald Alexander Pauley, Daniel Allen Wilkin, II, Ming Xie
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Publication number: 20160046952Abstract: Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.Type: ApplicationFiled: August 14, 2015Publication date: February 18, 2016Applicant: Wisconsin Alumni Research FoundationInventors: Christopher Todd Hittinger, William Gerald Alexander
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Patent number: 9239062Abstract: A fan blade for a gas turbine engine includes: a straight axial dovetail, an airfoil, and a transition section disposed between the dovetail and the airfoil, the fan blade having opposed pressure and suction sides, and further including at least one shoulder protruding from a nominal surface of a selected one of the pressure and suction sides, wherein the at least one shoulder includes a boss defining a side face, and an upper section extending radially outward from the boss and tapering inward to join a nominal surface of the selected side.Type: GrantFiled: September 10, 2012Date of Patent: January 19, 2016Assignee: General Electric CompanyInventors: Jorge Orlando Lamboy, Nicholas Joseph Kray, Gerald Alexander Pauley, Qiang Li, Daniel Allen Wilkin, II, Tod Winton Davis
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Publication number: 20150182646Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: ApplicationFiled: March 13, 2015Publication date: July 2, 2015Applicant: UNIVERSITY OF STRATHCLYDEInventors: John Galloway Anderson, Michelle MacLean, Gerald Alexander Woolsey, Scott John MacGregor
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Patent number: 9039966Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.Type: GrantFiled: July 28, 2006Date of Patent: May 26, 2015Assignee: University of StrathclydeInventors: John Galloway Anderson, Michelle Maclean, Gerald Alexander Woolsey, Scott John MacGregor
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Patent number: 9043041Abstract: The acceleration of a mobile asset is sensed and compared to threshold acceleration levels when the speed of the mobile asset is above a threshold speed. When the acceleration exceeds a threshold a report is created allowing aggressive driving behavior to be logged.Type: GrantFiled: April 13, 2011Date of Patent: May 26, 2015Assignee: Webtech Wireless Inc.Inventors: Richard Ernest Willis, Richard Ian McIntyre, Gerald Alexander West, Peter Robert Henderson McConnell