Patents by Inventor Gerald Boquet

Gerald Boquet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170216360
    Abstract: The disclosure relates to methods and compositions for improving homing of cells including mesenchymal stem cells (MSCs). Compositions include compounds described herein as capable of inducing expression by MSCs of cell surface homing ligand molecules such as CD1 la, promoting increased firm adhesion by MSCs in an in vitro shear flow assay, increasing binding to an adhesion molecule such as E-selectin or ICAM-1, and/or demonstrating anti-inflammatory activity upon in vivo systemic administration in cell therapy using human MSCs. Also described are screening methods to identify small molecule compounds for improving a homing function of MSCs.
    Type: Application
    Filed: January 21, 2015
    Publication date: August 3, 2017
    Inventors: Brigitte Benhamou, Gerald Boquet, Jean-Francois Deleuze, Jeffrey M. Karp, Oren Levy, Charles P. Lin, Luke J. Mortensen, Christelle Perrault, Jidong Zhang