Patents by Inventor Gerald Both

Gerald Both has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulatory constructs comprising intron 3 of prostate specific membrane antigen gene
    Publication number: 20060183229
    Abstract: The invention provides a recombinant vector comprising an ovine adenovirus genome and a sequence encoding a heterologous polypeptide, wherein the sequence encoding the heterologous polypeptide is inserted between E4 and E3 transcription units of the ovine adenovirus genome.
    Type: Application
    Filed: December 20, 2005
    Publication date: August 17, 2006
    Inventors: Peter Molloy, Fujiko Watt, Gerald Both
  • Composition and method for killing of tumours
    Publication number: 20060177423
    Abstract: The present invention provides a method of treating a solid tumour in a subject, the method comprising the following steps (i) delivering to the solid tumour a composition comprising an engineered ovine atadenovirus; and (ii) administering a prodrug to the subject, wherein the engineered ovine atadenovirus comprises a promoter and a gene encoding an enzyme which converts the prodrug to a cytotoxic metabolite, the gene being under control of the promoter.
    Type: Application
    Filed: March 28, 2003
    Publication date: August 10, 2006
    Inventors: Gerald Both, Trevor Lockett, Peter Molloy, Fiona Cameron, Pamela Russell, Rosetta Martiniello-Wilks, Minoo Moghaddam, Ian Smith