Patents by Inventor Gerald Brooks

Gerald Brooks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
    Patent number: 8071592
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: December 6, 2011
    Assignee: Glaxo Group Limited
    Inventors: Lluis Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J Remuiñan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Tryclic nitrogen containing compounds and their use as antibacterials
    Patent number: 7732461
    Abstract: Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: June 8, 2010
    Assignee: Glaxo Group Limited
    Inventors: Gerald Brooks, Ilaria Giordano, Alan Joseph Hennessy, Neil David Pearson
  • AZATRICYCLIC COMPOUNDS AND THEIR USE
    Publication number: 20100004230
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 7, 2010
    Applicant: GLAXO GROUP LIMITED
    Inventors: Gerald Brooks, Timothy James Miles, Neil David Pearson
  • DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES
    Publication number: 20090270374
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 18, 2007
    Publication date: October 29, 2009
    Inventors: Llius Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A. Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J. Remuinan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B. Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Tryclic Nitrogen Containing Compounds and their Use as Antibacterials
    Publication number: 20090137568
    Abstract: Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.
    Type: Application
    Filed: April 25, 2007
    Publication date: May 28, 2009
    Inventors: Gerald Brooks, Ilaria Giordano, Alan Joseph Hennessy, Neil David Pearson
  • Nitrogen-containing bicycle heterocycles for use as antibacterials
    Publication number: 20070135422
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: November 22, 2006
    Publication date: June 14, 2007
    Inventors: Gerald Brooks, David Davies, Graham Jones, Roger Markwell, Neil Pearson
  • Nitrogen-containing bicyclic heterocycles for use as antibacterials
    Patent number: 7141564
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: November 28, 2006
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Gerald Brooks, David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Antibacterial agents
    Publication number: 20060041123
    Abstract: Quinoline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans.
    Type: Application
    Filed: December 17, 2003
    Publication date: February 23, 2006
    Inventors: Jeffrey Axten, Gerald Brooks, Pamela Brown, David Davies, Timothy Gallagher, Roger Markwell, William Miller, Neil Pearson, Mark Seefeld
  • 2-Hydroxy-mutilin carbamate derivatives for antibacterial use
    Patent number: 6972297
    Abstract: 2-(S)-hydroxymutilin carbamate derivatives of formula (I), in which R1 is a 5- or 6-membered optionally substituted heteroaryl group; and R2 is vinyl or ethyl, are useful in the treatment of bacterial infections
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: December 6, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Gerald Brooks, Eric Hunt, Steven Howard
  • Heterocyclic mutilin esters and their use as antibacterials
    Patent number: 6878704
    Abstract: Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: April 12, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Steven Aitken, Gerald Brooks, Steven Dabbs, Colin Henry Frydrych, Steven Howard, Eric Hunt
  • Nitrogen-containing bicyclic heterocycles for use as antibacterials
    Publication number: 20040171620
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: April 6, 2004
    Publication date: September 2, 2004
    Inventors: Gerald Brooks, David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Heterocyclic mutilin esters and their use as antibacterials
    Publication number: 20040058937
    Abstract: Pleuromutilin compounds of the formula: 1
    Type: Application
    Filed: October 17, 2003
    Publication date: March 25, 2004
    Inventors: Steven Aitken, Gerald Brooks, Steven Dabbs, Colin Henry Frydrych, Steven Howard, Eric Hunt
  • 2-Hydroxy-mutilin carbamate derivatives for antibacterial use
    Publication number: 20030114674
    Abstract: 1 2-(S)-hydroxymutilin carbamate derivatives of formula (I), in which R1 is a 5- or 6-membered optionally substituted heteroaryl group; and R2 is vinyl or ethyl, are useful in the treatment of bacterial infections.
    Type: Application
    Filed: October 4, 2002
    Publication date: June 19, 2003
    Inventors: Gerald Brooks, Eric Hunt, Steven Howard
  • Penem compounds
    Patent number: 4931434
    Abstract: Compounds of the general formula (II): ##STR1## in which N.sup.+ denotes an unsubstituted or substituted nitrogen-containing heterocyclyl ring bonded to the remainder of the molecule through a ring nitrogen atom and carrying a positive charge on said nitrogen atom;and the wavy line denotes either the E- or Z-isomeric position,are novel and are useful in the treatment of antibacterial infection in humans or animals.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: June 5, 1990
    Assignee: Beecham Group p.l.c.
    Inventors: Nigel J. P. Broom, Gerald Brooks, Brian P. Clarke
  • Penem compounds
    Patent number: 4923856
    Abstract: Compounds of the general formula (II): ##STR1## and pharmaceutically acceptable salts and in-vivo hydrolysable esters thereof, in whichR denotes a hydrogen atom or an in vivo hydrolysable acyl group;and the wavy line denotes either the E- or Z-isometric position,are novel compounds which exhibit .beta.-lactamase inhibitory action and have antibacterial properties.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: May 8, 1990
    Assignee: Beecham Group p.l.c.
    Inventors: Nigel J. P. Broom, Gerald Brooks, Steven Coulton
  • Clavulanic acid derivatives their preparation and use
    Patent number: 4372962
    Abstract: The compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts and in-vivo hydrolysable esters thereof wherein X is a sulphur atom or SO or SO.sub.2 group and R is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms have been found to be .beta.-lactamase inhibitors and antibacterial agents. Their preparation and use is described.
    Type: Grant
    Filed: May 13, 1980
    Date of Patent: February 8, 1983
    Assignee: Beecham Group Limited
    Inventors: John S. Davies, Gerald Brooks
  • Process for preparing 7-aminocephalosporanic acid derivatives
    Patent number: 4115646
    Abstract: The use of an iodolactone as an esterifying derivative in the preparation of lactonyl esters of cephalosporins substantially reduces double bond migration during the esterification reaction.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: September 19, 1978
    Assignee: Beecham Group Limited
    Inventors: Peter Hubert Bentley, Gerald Brooks