Abstract: Described herein are formulations of a somatostatin modulator, methods of making such formulations, and methods of using such formulations in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Described herein are formulations of a somatostatin modulator, methods of making such formulations, and methods of using such formulations in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Described herein are formulations of a somatostatin modulator, methods of making such formulations, and methods of using such formulations in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Described herein are formulations of a somatostatin modulator, methods of making such formulations, and methods of using such formulations in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Described herein are formulations of a somatostatin modulator, methods of making such formulations, and methods of using such formulations in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: A method and apparatus for absorbing energy during a frontal collision of a vehicle, through the use of a front frame structure having main frame rails that include several deformable and non-deformable sections which are connected by selectively crushable junctures that are configured to predispose one or more of the junctures and sections to pivot selectively outward, rearward and upward, in a predetermined manner, during the collision. The front frame structure also includes an engine cradle, attached below the main frame rails, and having a pair of side rails that include forward and rear crushable junctures joined by non-deformable intermediate sections, with the crushable junctures of the main frame rails and engine cradle side rails being configured to predispose the intermediate sections of the engine cradle side rails to move downward and rearward during the collision.

Abstract: Methods, apparatus and precursors for producing substantially water-free silica soot, preforms and glass. The methods and apparatus make substantially water-free fused silica preforms or glass by removing water as a reaction product, removing water from the atmosphere, removing water from the transport process, or combinations thereof. In a first embodiment, substantially water-free soot, preforms or glass are achieved by using a hydrogen-free fuel, such as carbon monoxide, in the deposition process. In another embodiment, a soot producing burner has parameters that enable operation on a substantially hydrogen-free fuel. End burners, which minimize water production, are also described. Such water-free methods are useful in depositing fluorine-doped soot because of the low water present and the efficiency in which fluorine is incorporated. In another embodiment, glassy barrier layer methods and apparatus are described for minimizing dopant migration, especially fluorine.

Abstract: A dual-sectioned automotive propeller shaft features a weakened area in a first section. Under an axial load, the first section buckles transversely to a longitudinal axis of the shaft to absorb substantially all of the energy exerted against the shaft. A second section of the shaft is thereby isolated from consequences of the axial load enabling its placement and proximity to other components mounted to the undercarriage of the vehicle.