Patents by Inventor Gerald Christopher O'Sullivan
Gerald Christopher O'Sullivan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100112003Abstract: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.Type: ApplicationFiled: June 5, 2009Publication date: May 6, 2010Inventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan
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Publication number: 20080311080Abstract: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.Type: ApplicationFiled: May 19, 2008Publication date: December 18, 2008Applicants: University College Cork - National University of Ireland, CorkInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan
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Patent number: 7390519Abstract: A Lactobacillus salivarius strain, AH102, AH103, AH105, AH109 or AH110 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.Type: GrantFiled: April 14, 2005Date of Patent: June 24, 2008Assignee: Alimentary Health LimitedInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan, Barry Kiely
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Patent number: 7195906Abstract: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.Type: GrantFiled: February 23, 2004Date of Patent: March 27, 2007Assignees: Enterprise Ireland (Trading as BioResearch Ireland), University College Cork--National University of IrelandInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan
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Patent number: 7186545Abstract: A strain of Lactobacillus salivarius isolated from resected and washed human gastrointestinal tract inhibits a broad range of Gram positive and Gram negative microorganisms and secretes a product having antimicrobial activity into a cell-free supernatant. The activity is produced only by, growing cells and is destroyed by proteinase K and pronase E, the inhibitory properties of the strain and its secretory products being maintained in the presence of physiological concentrations of human bile and human gastric juice. The strain exhibits a broad-spectrum of activity against bacteria including Listeria, Staphylococcus, including methocillin resistant St. aureus (MRSA), and Bacillus, but does not inhibit many closely related lactobacilli. An antimicrobial agent is obtained from the strain which has bacteriocin-like properties.Type: GrantFiled: June 26, 2003Date of Patent: March 6, 2007Assignees: Enterprise Ireland, University College Cork - National University of IrelandInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Gerardine Mary Thornton, Marian Mary Geraldine O'Sullivan
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Patent number: 6872411Abstract: A process for the manufacture of a probiotic cheese, such as Cheddar cheese, comprises adding a 0.0-5.5% inoculum of a strain of Lactobacillus paracasei, which is non-pathogenic, acid and bile tolerant and adherent to human epithelial cells, as a starter adjunct to cheese milk, said L. paracasei strain being capable of growing during the ripening phase to a level of 107 cfu/g or greater. The L. paracasei strains are found to grow and proliferate to high cell numbers (in excess of 108 cfu/g) in the cheese over eight months of ripening, even when added at a relatively low inoculum. The presence of the L. paracasei strains is found to have negligible effects on cheese composition, flavor and aroma.Type: GrantFiled: May 26, 1999Date of Patent: March 29, 2005Assignees: Enterprise Ireland, Teagasc, The Agriculture and Food Development AuthorityInventors: Reynolds Paul Ross, Gerald Francis Fitzgerald, John Kevin Collins, Gerald Christopher O'Sullivan, Catherine Gerardine Stanton
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Publication number: 20040214304Abstract: A strain of Lactobacillus salivarius isolated from resected and washed human gastrointestinal tract inhibits a broad range of Gram positive and Gram negative microorganisms and secretes a product having antimicrobial activity into a cell-free supernatant. The activity is produced only by, growing cells and is destroyed by proteinase K and pronase E, the inhibitory properties of the strain and its secretory products being maintained in the presence of physiological concentrations of human bile and human gastric juice. The strain exhibits a broad-spectrum of activity against bacteria including Listeria, Staphylococcus, including methocillin resistant St. aureus (MRSA), and Bacillus, but does not inhibit many closely related lactobacilli. An antirmicrobial agent is obtained from the strain which has bacteriocin-like properties.Type: ApplicationFiled: June 26, 2003Publication date: October 28, 2004Applicant: Enterprise Ireland and University College Cork-National University of Ireland, CorkInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Gerardine Mary Thornton, Marian Mary Geraldine O'Sullivan
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Publication number: 20040038379Abstract: A strain of Lactobacillus salivarius isolated from resected and washed human gastrointestinal tract inhibits a broad range of Gram positive and Gram negative microorganisms and secretes a product having antimicrobial activity into a cell-free supernatant. The activity is produced only by growing cells and is destroyed by proteinase K and pronase E, the inhibitory properties of the strain and its secretory products being maintained in the presence of physiological concentrations of human bile and human gastric juice. The strain exhibits a broad-spectrum of activity against bacteria including Listeria, Staphylococcus, including methocillin resistant St. aureus (MRSA), and Bacillus, but does not inhibit many closely related lactobacilli. An antimicrobial agent is obtained from the strain which has bacteriocin-like properties.Type: ApplicationFiled: June 26, 2003Publication date: February 26, 2004Applicants: Enterprise Ireland and University College Cork -, National University of Ireland, CorkInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Gerardine Mary Thornton, Marian Mary Geraldine O'Sullivan
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Publication number: 20030215467Abstract: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.Type: ApplicationFiled: March 17, 2003Publication date: November 20, 2003Applicant: Enterprise Ireland (Trading as Bioresearch Ireland and National University of Ireland, Cork.Inventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan
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Publication number: 20030170217Abstract: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.Type: ApplicationFiled: March 3, 2003Publication date: September 11, 2003Applicant: Enterprise Ireland (Trading as Bioresearch Ireland and National University of Ireland, Cork.Inventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan
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Publication number: 20030166257Abstract: Lactobacillus salivarius is useful in the prophylaxis or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer. The Lactobacillus salivarius is of human origin isolated from resected and washed human gastrointestinal tract. One such strain is UCC 118 described in WO-A-9835014.Type: ApplicationFiled: September 12, 2002Publication date: September 4, 2003Applicant: Enterprise IrelandInventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan
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Publication number: 20030113306Abstract: A Lactobacillus casei strain or a mutant or variant thereof isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. In particular a Lactobacillus casei strain, AH101, AH104, AH111, AH112 or AH113 or mutants or variants are thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.Type: ApplicationFiled: July 25, 2002Publication date: June 19, 2003Inventors: John Kevin Collins, Gerald Christopher O'sullivan, Liam O'Mahony, Fergus Shanahan, Barry Kiely
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Publication number: 20030092163Abstract: A Bifidobacterium strain, AH208, AH209, AH210, AH211, AH212 or AH214 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.Type: ApplicationFiled: July 25, 2002Publication date: May 15, 2003Inventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan, Barry Kiely
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Publication number: 20030091549Abstract: A Lactobacillus salivarius strain, AH102, AH103, AH105, AH109 or AH110 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.Type: ApplicationFiled: July 26, 2002Publication date: May 15, 2003Inventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan, Barry Kiely
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Publication number: 20020006432Abstract: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.Type: ApplicationFiled: July 13, 2001Publication date: January 17, 2002Inventors: John Kevin Collins, Gerald Christopher O'Sullivan, Liam O'Mahony, Fergus Shanahan