Patents by Inventor Gerald Curtis

Gerald Curtis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • methods for testing toxicity of substances using donated human organs or tissues
    Patent number: 8771930
    Abstract: Properties such as toxicity of substances may be determined by assaying properties, fates and effects of substances in an ex vivo metabolically active human organ or tissue under normothermic perfusion with a fluid containing a test substance. The data can be used as, for example, part of a submission to a government regulatory organization. Preferred methods use perfused endocrine gland organs or tissues to evaluate hormone or other bodily chemical disruption caused by substances and pre-donation diseased or injured organs or tissues.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: July 8, 2014
    Assignee: Lifeline Scientific, Inc.
    Inventors: Gerald Curtis, John Brassil, David Kravitz
  • Ex vivo methods for validating substance testing with human organs and/or tissues
    Patent number: 8765364
    Abstract: Methods of validating results of assessments of test substances using human-derived tissues and/or organs, particularly tissues and/or organs unsuitable for transplantation, include assessing the suitability of the organ and/or tissue for substance testing, as well as inter-organ variability and use of exogenous and/or endogenous controls.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: July 1, 2014
    Assignee: Lifeline Scientific, Inc.
    Inventors: Gerald Curtis, John Brassil, David Kravitz