Patents by Inventor Gerald D. Fischbach

Gerald D. Fischbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurotrophic factor
    Patent number: 5665862
    Abstract: The invention pertains to isolated neurotrophic factors, designated as ARIA, which are able to induce the formation of ion channels in a surface membrane of a cell. The amino acid sequence of the neurotrophic factors includes an EGF-like domain, and a second amino acid sequence encoded by at least a portion of an exon of the neurotrophic factor gene normally expressed in a neuronal cell, especially a nerve cell. The neurotrophic factor is distinct from, and essentially unrelated to, the chicken prion-like protein previously identified.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: September 9, 1997
    Assignee: President and Fellows of Harvard College
    Inventors: Gerald D. Fischbach, Douglas L. Falls, Kenneth M. Rosen, Gabriel Corfas
  • DNA encoding a protein which copurifies with acetylcholine receptor inducing activity and uses therefor
    Patent number: 5237056
    Abstract: Described herein is the cloning and characterization of DNA encoding a protein which appears at an early stage in spinal cord development, is concentrated in motor neurons, and appears to have a role in neuromuscular junction formation. This protein copurifies with an activity which induces acetylocholine receptor synthesis in muscle fibers. A method for enhancing neurotransmitter receptor synthesis or accumulation in cells, especially that of the acetylcholine receptor, is also described.
    Type: Grant
    Filed: May 29, 1991
    Date of Patent: August 17, 1993
    Assignee: President and Fellows of Harvard College
    Inventor: Gerald D. Fischbach