Patents by Inventor Gerald E. Bossard

Gerald E. Bossard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ruthenium containing phthalocyanin photosensitizers
    Patent number: 5556849
    Abstract: Water soluble salt or acid forms of a transition metal phthalocyanine of formula ##STR1## where M is a transition metal, X is H, alkyl, alkoxy, halide or X's together form --C.sub.4 H.sub.4 --, each R is a ligand with a solubilizing group, and Q is N or --CY-- where Y is H, alkyl, alkoxy or halide, are surprisingly active in tests indicating photodynamic properties. Novel compounds, preparative methods and pharmaceutical compositions are included.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: September 17, 1996
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Michael J. Abrams, Robert C. Brooks, Gerald E. Bossard, Jean F. Vollano
  • Anti-tumor platinum complexes
    Patent number: 5547982
    Abstract: Platinum complexes, having anti-tumor activity, which include at least one functional ketone group or aldehyde, optionally conjugated as a linkable hydrazone complex. The functional ketone and aldehyde groups and the functionalized hydrazone complexes are linkable to antibodies, proteins, peptides and compounds having free amine, hydrazine or hydrazide functionality. Such agents are useful as targeted site-specific or disease specific chemotherapeutic agents.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: August 20, 1996
    Assignee: Johnson Matthey, Inc.
    Inventors: Michael J. Abrams, Gerald E. Bossard, Robert C. Brooks, Geoffrey W. Henson, Jean F. Vollano
  • Platinum complexes
    Patent number: 5519155
    Abstract: Pt(IV) complexes of formula I, ##STR1## where X is halide, pseudohalide or OH,R.sup.1 and R.sup.2 are H, C.sub.1 to C.sub.6 alkyl, cycloalkyl, aryl or R.sup.1 NH.sub.2 is a heterocyclic hydrogen donor, and may be the same or different,R.sup.3 and R.sup.4 are H, C.sub.1 to C.sub.5 alkyl, cycloalkyl or aryl and may be the same or different, andR.sup.5 is H, Me or Et,have activity in vitro and in vivo against cancer cells.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: May 21, 1996
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Christopher F. J. Barnard, Gerald E. Bossard
  • Invitroinhibition of the HIV virus with ionic tungstoniobate compounds
    Patent number: 5512305
    Abstract: Tungstoniobate compounds containing an ion of general formulaA.sub.x W.sub.y Nb.sub.a O.sub.b !.sup.p- Iwhere A=P, Si, Ge, x=0 or an integer from 1 to 10, y is an integer from 1 to 10, y is an integer from 1 to 40, a is an integer from 1 to 8, b is an integer from 15 to 150, and p is an integer dependent upon the nature and oxidation state of element A, have been found to be active against viruses including especially HIV and Herpes Simplex. Pharmaceutical compositions and methods of treatment are disclosed.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: April 30, 1996
    Inventors: Michael J. Abrams, Gerald E. Bossard, Craig L. Hill, Raymond F. Schinazi, Brian R. C. Theobald