Abstract: A cooling handpiece and method for use in therapeutic, cosmetic or aesthetic, diagnostic, exploratory, interventional or other medical procedures, the handpiece for use in conjunction with a controllable energy source such as coherent light, non-coherent light or laser light, ultrasound energy, radio frequency energy and other types of electromagnetic and mechanical energy, the handpiece comprising a main body portion adapted for directing the energy to target tissue, the main body portion further adapted for receiving a removable reservoir containing coolant fluid, the reservoir having an attachment means for releasable attachment of the reservoir to the handpiece, and the handpiece having a controllable valve for delivery of a portion of the coolant fluid to the target tissue.