Abstract: A cryoablation catheter assembly is described. The assembly comprises (a) an inlet for receiving an input flow of refrigerant fluid, (b) a cryo-applicator, (c) a flow splitter configured to split the input flow into a therapeutic flow portion and a precooling flow portion, and (d) a precooling arrangement configured to precool the therapeutic flow portion and guide the precooled therapeutic flow portion towards the cryo-applicator, wherein the precooling arrangement comprises a heat exchanger configured to apply an adjustable precooling power from the precooling flow portion to the therapeutic flow portion. Furthermore, a cryoablation system and a method are described.

Abstract: An ablation device including an ablation applicator having a first applicator end portion, a second applicator end portion, and an elongate portion, a first catheter having a first distal end portion and a first proximate end portion, the first distal end portion being coupled to the first applicator end portion, and a second catheter having a second distal end portion and a second proximate end portion, the second distal end portion being coupled to the second applicator end portion to supply an ablation medium to the ablation applicator, the ablation applicator forms an applicator shape having an applicator size in a plane perpendicular to a longitudinal axis of the first catheter, and the coupling between the first distal end portion and the first applicator end portion transfers a rotational force applied to the first proximate end portion to the ablation applicator and thereby cause the applicator size to change.

Abstract: An ablation applicator for an ablation device for ablating tissue of a blood vessel having a tubular body defining an inner lumen to which an ablation medium is conductible, a control mechanism for converting the tubular body between a passive operation mode for inserting the ablation applicator into the blood vessel and an active operation mode for ablating tissue of the blood vessel, and an ablation medium supply line for supplying the ablation medium to the inner lumen and positioned within the inner lumen and having a number of openings for passing the ablation medium from the ablation medium supply line to the inner lumen for thermally contacting the ablation medium with the tubular body wherein at least some of the openings are distributed along the ablation medium supply line with a predetermined spacing between neighboring openings.

Abstract: An ablation applicator for an ablation device for ablating tissue of a blood vessel having a tubular body defining an inner lumen to which an ablation medium is conductable, a control mechanism for converting the tubular body between a passive operation mode for inserting the ablation applicator into the blood vessel and an active operation mode for ablating tissue of the blood vessel, and an ablation medium supply line for supplying the ablation medium to the inner lumen and positioned within the inner lumen and having a number of openings for passing the ablation medium from the ablation medium supply line to the inner lumen for thermally contacting the ablation medium with the tubular body wherein at least some of the openings are distributed along the ablation medium supply line with a predetermined spacing between neighboring openings.

Abstract: A catheter device for ablating biological material is described. The catheter device comprises (a) a longitudinal structure; (b) an applicator for ablating the biological material, wherein the applicator is installed at the longitudinal structure; (c) a first electrode being attached to the longitudinal structure; (d) a second electrode being attached to the longitudinal structure; (e) an interface being connected directly or indirectly to the longitudinal structure; (f) a first lead electrically connecting the first electrode with the interface; and (g) a second lead electrically connecting the second electrode with the interface. The interface is configured for electrically connecting the first lead and the second lead with a measurement device for electrically stimulating the first electrode and the second electrode and for detecting an electric quantity being associated with an electric response of an biological material being located in between the two stimulated electrodes.

Abstract: A valve slide for a valve unit used as an insufflation and purging valve, which valve slide has a proximal actuating section, which is led through a holder and has an actuating knob. The actuating knob is supported on the holder via a compression spring on the one hand, and wherein an annular projection of the valve slide interacts with the holder as a stop acting in the axial direction on the other hand. At the distal control section of the valve slide, sealing rings are provided, which project radially beyond the valve slide, an outer lateral surface of the distal control section, apart from radial guide sections possibly provided on the latter and the projection, is formed with a smooth wall, and the sealing rings are connected integrally to the smooth-walled outer lateral surface.

Abstract: An ablation device comprising an ablation applicator adapted for ablating material from an object upon delivery of an ablation medium to the ablation applicator in an ablation mode, an ablation medium supply line adapted for supplying the ablation medium to the ablation applicator in the ablation mode, an ablation medium drain line adapted for draining the ablation medium received from the ablation applicator in the ablation mode, and a closure mechanism adapted for selectively enclosing a predefined volume in a fluidic path upon operating the ablation device in a no-flow mode or upon detecting a leak in the fluidic path, the fluidic path including the ablation applicator and being defined between the ablation medium supply line and the ablation medium drain line.

Abstract: An ablation device is described. The ablation device comprises (a) an ablation catheter having an ablation applicator, and (b) a sheath comprising an elongate tubular member and a dilatable member arranged at the distal end of the elongate tubular member. The elongate tubular member defines an inner lumen adapted to receive the ablation catheter having the ablation applicator, wherein the elongate tubular member comprises an opening at a distal end thereof, the opening being adapted to allow the ablation applicator to extend in front of the distal end. The elongate tubular member comprises an outer wall in which a canal structure is formed, wherein the canal structure is in fluid communication with the dilatable member, and wherein the canal structure is adapted to supply fluid to the dilatable member in order to dilate it and to discharge fluid from the dilatable member in order to compress it. The ablation catheter is slidably arranged within the inner lumen of the sheath.

Abstract: A catheter device for ablating biological material is described. The catheter device comprises (a) a longitudinal structure; (b) an applicator for ablating the biological material, wherein the applicator is installed at the longitudinal structure; (c) a first electrode being attached to the longitudinal structure; (d) a second electrode being attached to the longitudinal structure; (e) an interface being connected directly or indirectly to the longitudinal structure; (f) a first lead electrically connecting the first electrode with the interface; and (g) a second lead electrically connecting the second electrode with the interface. The interface is configured for electrically connecting the first lead and the second lead with a measurement device for electrically stimulating the first electrode and the second electrode and for detecting an electric quantity being associated with an electric response of an biological material being located in between the two stimulated electrodes.

Abstract: An ablation applicator for an ablation device for ablating tissue of a blood vessel having a tubular body defining an inner lumen to which an ablation medium is conductable, a control mechanism for converting the tubular body between a passive operation mode for inserting the ablation applicator into the blood vessel and an active operation mode for ablating tissue of the blood vessel, and an ablation medium supply line for supplying the ablation medium to the inner lumen and positioned within the inner lumen and having a number of openings for passing the ablation medium from the ablation medium supply line to the inner lumen for thermally contacting the ablation medium with the tubular body wherein at least some of the openings are distributed along the ablation medium supply line with a predetermined spacing between neighboring openings.

Abstract: A tool system having a hand-held machine tool including a tool holder for receiving an insert tool; and a mounting interface configured for mounting thereon: an angle attachment that includes an angle locking section for locking on the mounting interface and an angle drive unit; and an eccentric attachment that includes an eccentric locking section for locking on the mounting interface and an eccentric drive unit.

Abstract: An ablation applicator for an ablation device, the ablation applicator comprising a tubular body defining an inner lumen to which an ablation medium is conductible, wherein the tubular body comprises a matrix accommodating a plurality of particles.

Abstract: An ablation device comprising an ablation applicator adapted for ablating material from an object upon delivery of an ablation medium to the ablation applicator in an ablation mode, an ablation medium supply line adapted for supplying the ablation medium to the ablation applicator in the ablation mode, an ablation medium drain line adapted for draining the ablation medium received from the ablation applicator in the ablation mode, and a closure mechanism adapted for selectively enclosing a predefined volume in a fluidic path upon operating the ablation device in a no-flow mode or upon detecting a leak in the fluidic path, the fluidic path including the ablation applicator and being defined between the ablation medium supply line and the ablation medium drain line.

Abstract: An ablation device comprising an ablation applicator adapted for ablating material from an object upon delivery of an ablation medium to the ablation applicator in an ablation mode, an ablation medium supply line adapted for supplying the ablation medium to the ablation applicator in the ablation mode, an ablation medium drain line adapted for draining the ablation medium received from the ablation applicator in the ablation mode, and a closure mechanism adapted for selectively enclosing a predefined volume in a fluidic path upon operating the ablation device in a no-flow mode or upon detecting a leak in the fluidic path, the fluidic path including the ablation applicator and being defined between the ablation medium supply line and the ablation medium drain line.

Abstract: A handle for an ablation device, the handle comprising a positioning control handle part adapted to be coupled to a positioning catheter of the ablation device and adapted to position the positioning catheter in an object, and an ablation control handle part adapted to be coupled to an ablation catheter of the ablation device and adapted to ablate material of the object using the ablation catheter, wherein the positioning control handle part and the ablation control handle part are adapted to be separable from one another.

Abstract: An ablation device comprising a positioning catheter adapted to be positionable in a heart and comprising a fixation mechanism for fixing the positioning catheter in the heart, and an ablation catheter adapted to ablate material of the heart using the ablation catheter, wherein the ablation catheter is designed to ablate tissue along an isthmus of the heart, wherein the positioning catheter and the ablation catheter are provided to be movable relative to one another.

Abstract: A tool system having a hand-held machine tool including a tool holder for receiving an insert tool; and a mounting interface configured for mounting thereon: an angle attachment that includes an angle locking section for locking on the mounting interface and an angle drive unit; and an eccentric attachment that includes an eccentric locking section for locking on the mounting interface and an eccentric drive unit.

Abstract: An ablation applicator for an ablation device, the ablation applicator comprising a tubular body defining an inner lumen to which an ablation medium is conductible, wherein the tubular body comprises a matrix accommodating a plurality of particles.

Abstract: The device for mechanical lithotripsy and removal of stones that form in the bile duct or urinary system has a stone collection basket at a distal end of a tube and two actuators at the proximal end of the tube. A cable runs through the tube and connects each actuator to the basket. The actuators are screw drives and form a common structural unit that is concentric to the tube and the cable. One actuator controls the opening and closing of the basket while the other actuator controls the force transmitted through the cable to the basket to allow for crushing of the stone in the basket.

Abstract: A cooling device for cooling a catheter, the cooling device comprising a main cooling unit adapted for supplying the catheter with a main cooling medium and a precooling unit adapted for precooling the main cooling medium before supply of the main cooling medium to the catheter, wherein the main cooling unit comprises a cooling pathway through which a fluid is guidable as the main cooling medium, and comprising a control unit adapted for automatically controlling the main cooling unit and the precooling unit to perform a predetermined cooling procedure, wherein the control unit is adapted for activating the precooling unit before activating a supply of the main cooling medium by the main cooling unit to the catheter.