Abstract: The present application relates to methods of personalized pharmaceutics. More specifically, the invention relates to methods for the production of pharmaceutical dosage forms, which are produced by 3D and/or 2D printing, whereby a wide variety of parameters relevant to the administration of the dosage form can be changed depending on the analysis of patient-and disease-specific data and can be adapted in the course of the patient's treatment. In this way, the quality of treatment for the patient can be improved in the future and significantly increased from the point of view of patient safety.

Abstract: The invention relates to a method performed by at least one apparatus, the method comprising: Obtaining release information representative of a release of a medical module of a medical kit comprising one or more medical modules; and releasing or triggering release of the medical module of the medical kit. The invention further relates to a method performed by at least one apparatus, the method comprising obtaining a user input of a user indicating the release of a medical module of a medical kit comprising one or more medical modules; and providing release information representative of the release of the medical module of the medical kit. The invention also relates to corresponding apparatuses, computer program products and computer-readable storage media.

Abstract: The present invention relates to a method and to a device for producing solid, at least semisolid dosage forms of pharmaceutical active agents, nutraceutical active agents and/or dietary supplemental active agents, wherein the dosage form is generated in an additive fashion by depositing a building substance in the form of dots.

Abstract: The invention relates to a method performed by at least one apparatus, the method comprising: Obtaining release information representative of a release of a medical module of a medical kit comprising one or more medical modules; and releasing or triggering release of the medical module of the medical kit. The invention further relates to a method performed by at least one apparatus, the method comprising obtaining a user input of a user indicating the release of a medical module of a medical kit comprising one or more medical modules; and providing release information representative of the release of the medical module of the medical kit. The invention also relates to corresponding apparatuses, computer program products and computer-readable storage media.

Abstract: The present invention relates to solid or semi-solid dosage forms made of solidified filament structures having different compositions. At least some of the filament structures contain at least one pharmaceutical active agent, nutraceutical active agent and/or dietary supplemental active agent. Other filament structures of the dosage forms can contain the same active agent e.g., in different concentrations, a different active agent, or no active agent. The invention also relates to a method for 3D printing of the dosage forms.

Abstract: The invention relates to a method for producing solid or semi-solid dosage forms of pharmaceutical active ingredients. According to the method, an active-ingredient-free carrier structure is arranged in a 2D or 3D printing device and at least one pharmaceutical active ingredient is applied to at least one portion of the carrier structure by way of a 2D or 3D printing method carried out by the printing device. The invention also relates to semi-solid or solid dosage forms that are producible by the method according to the invention.

Abstract: The present invention relates to an additive method for the production of solid or semi-solid two- or three-dimensional objects containing one of more pharmaceutical active agent(s), as well as to the objects produced by said method, such as semi-solid or solid dosage forms or medical devices. The method is a three-dimensional printing method in which individual defined volume increments are printed, which can be selected essentially freely as regards contained active agents, used carrier materials, shape, size, color, concentrations of active agents, and arrangement in the produced object.

Abstract: The invention relates to a method performed by at least one apparatus, the method comprising: Obtaining release information representative of a release of a medical module of a medical kit comprising one or more medical modules; and releasing or triggering release of the medical module of the medical kit. The invention further relates to a method performed by at least one apparatus, the method comprising obtaining a user input of a user indicating the release of a medical module of a medical kit comprising one or more medical modules; and providing release information representative of the release of the medical module of the medical kit. The invention also relates to corresponding apparatuses, computer program products and computer-readable storage media.

Abstract: The present invention provides an oral tablet comprising glatiramer acetate in an amount from about 10 percent to about 60 percent by weight and one or more gel forming agents in a total amount up to about 90 percent by weight. The present invention also provides a method of delivering glatiramer acetate across a buccal membrane comprising orally administering an oral tablet of any one of the embodiments.

Abstract: A pneumatic suspension and damping arrangement (100) is fixedly mounted on the chassis at the upper region and to the wheel mount at the lower region thereof. The arrangement includes two hermetically closed air springs (101, 102) filled with pressurized gas, whose volumes can be changed and which are connected via an air connection (134) to a pressurized gas source. The air springs are each enclosed by a movable wall formed by a flexible member (116, 124) and each roll off on a roll-off contour and are connected to each other via a throttle element (108) through which the gas can flow in two directions. The air springs are arranged one above the other and the roll-off contour of the first air spring (101) is defined in such a way by the second air spring (102) that the first air spring (101) rolls off on the second air spring (102). A connecting element of the upper cover (104) ) with the roll-off piston (128) of the second air spring (102) runs outside of the two air springs (101, 102).

Abstract: A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble in gastric and intestinal juices, where the particles have as core a homogeneous mixture comprising an active pharmaceutical ingredient and a polymer insoluble in gastric and intestinal juices, with an average internal pore diameter not exceeding 35 ?m, makes efficient and pH-independent delaying of release possible even with comparatively small amounts of polymer. It is additionally distinguished by a long shelf life and is particularly suitable also for nonspherical particles.

Abstract: The present invention relates to a method for the production of a ribavirin-containing granulate, comprising the production of a granulate solution, comprising mixing of a binding agent with an isopropanol/water- or ethanol/water-mixture, stirring of the granulate solution into a mixture of ribavirin-powder with a hydrophilic or swellable solid adjuvant, and sieving and drying the so-obtained granulate, which is characterised in that the portion of isopropanol or ethanol of the alcohol/water-mixture is between 65% to 85% by weight. Based on this granulate, a ribavirin-tablet can be produced that can be used for the treatment of diseases, such as HCV.

Abstract: A pneumatic suspension and damping arrangement (100) is especially for vehicles and can be fixedly mounted on the chassis at the upper region and to the wheel mount at the lower region thereof. The pneumatic suspension and damping arrangement includes at least two hermetically closed air springs (101, 102) filled with pressurized gas, whose volumes can be changed and which are connected via an air connection (134) to a pressurized gas source. The air springs are each enclosed by a movable wall formed by a flexible member (116, 124) and each roll off on a roll-off contour and are connected to each other via a throttle element (108) through which the gas can flow in two directions. The air springs are arranged one above the other and the roll-off contour of the first air spring (101) is defined in such a way by the second air spring (102) that the first air spring (101) rolls off on the second air spring (102).

Abstract: An automatic message, time and temperature announcement system wherein the signals to be announced are stored in digitized form in a random access memory (32). Under control of a CPU (15), blocks of digitized speech signals are provided to a FIFO (35) and from there to a CVSD digital to analog converter (37), the output of which is coupled (41) to a plurality of telephone trunks (42). A digital counter timer peripheral (26) is used to maintain a count of the time of day (32) and the frequency output (49) of a voltage to frequency converter (48) connected to a temperature sensor (40). Loading of digitized speech signals, correction factors for time of day, and other controls may be accomplished remotely through a data link (27, 30) from a standard voice grade telephone line (31).