Patents by Inventor Gerald Joseph Litt

Gerald Joseph Litt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Catalyzed reporter deposition
    Patent number: 5731158
    Abstract: The present invention concerns a method to catalyze reporter deposition to improve detection or quantitation of an analyte in a sample by amplifying the detector signal which comprises reacting an analyte dependent enzyme activation system with a conjugate consisting of a detectably labeled substrate specific for the enzyme system, said conjugate reacts with the analyte dependent enzyme activation system to form an activated conjugate which deposits substantially wherever receptor for the activated conjugate is immobilized, said receptor not being reactive with the analyte dependent enzyme activation system.In another embodiment the invention concerns an assay for detecting or quantitating the presence or absence of an analyte in a sample using catalyzed reporter deposition to amplify the reporter signal.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: March 24, 1998
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Norman Bobrow, Gerald Joseph Litt