Patents by Inventor Gerald Kirchner

Gerald Kirchner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic processes for preparing (S)-cyanohydrins
    Patent number: 6337196
    Abstract: An enantioselective process for the preparation of the (S)-enantiomer of an optically active cyanohydrin by reaction of an aldehyde or of a ketone with a cyanide group donor, in which the aldehyde or the ketone is reacted with a cyanide group donor in an organic diluent in the presence of a recombinant (S)-hydroxynitrile lyase from Hevea brasiliensis and the (S)-cyanohydrin formed is isolated from the reaction mixture.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: January 8, 2002
    Assignee: DSM Fine Chemicals Austria Nfg GmbH & CoKG
    Inventors: Gerald Kirchner, Irma Wirth, Christian Werenka, Herfried Griengl, Michael Schmidt
  • Process for the preparation of disodium benzyloxycarbonyl-L-aspartate from fumaric acid
    Patent number: 5902737
    Abstract: A process for the preparation of disodium Z-L-aspartate from fumaric acid, in whicha) fumaric acid is reacted with ammonia in an inert diluent in the presence of aspartase or aspartase-producing microorganisms to give ammonium L-aspartate thenb) the ammonium L-aspartate-containing solution is treated with sodium hydroxide, forming, depending on the amount of sodium hydroxide used, the mono- or disodium L-aspartate or a mixture thereof, andc) the eliminated ammonia is returned to a fumaric acid suspension, which is used as starting solution for further enzymatic reactions, and thend) the residual mono and/or disodium L-aspartate-containing solution is reacted with benzyloxycarbonyl chloride at a pH of between 9 and 14, with the simultaneous addition of sodium hydroxide, to form disodium Z-L-aspartate.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: May 11, 1999
    Assignees: DSM Fine Chemicals Austria GmbH, Holland Sweetener Company V.o.V.
    Inventors: Gerald Kirchner, Erik Salzbrenner, Christian Werenka, Wilhelmus Boesten
  • Enzymatic production of optical isomers of 2-halopropionic acids
    Patent number: 4601987
    Abstract: A method of resolving racemic 2-halopropionic acids by lipase-catalyzed asymmetric esterification in an organic medium is disclosed.
    Type: Grant
    Filed: February 27, 1985
    Date of Patent: July 22, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: Alexander M. Klibanov, Gerald Kirchner