Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is alkyl of 1 to 3 carbon atoms, inclusive; wherein R.sub.2 is hydrogen, methyl or ethyl; wherein R.sub.3 is hydrogen, fluoro, chloro, bromo, nitro and --CF.sub.3 ; and wherein A is phenyl, o-chlorophenyl, o-fluorophenyl, 2,6-difluorophenyl, and 2-pyridyl, are prepared by treating a hydrazino compound of the formula: ##STR2## with a carbonyl compound II: ##STR3## wherein R.sub.1 is defined as above, and R', R" are alkyl of 1 to 3 carbon atoms, inclusive or the group ##STR4## is a cyclic acetal to give a compound of formula III: ##STR5## wherein R.sub.1, R.sub.2, R.sub.3, R', R" and Ar are defined as above, and cyclizing compound III to give the compound IV above.Compounds III and IV, including the pharmacologically acceptable acid addition salt of these compounds, have sedative, anxiolytic and muscle-relaxing activity and can be used for the treatment of anxieties or muscle strains of mammals, including man.

Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is alkyl of 1 to 3 carbon atoms, inclusive; wherein R.sub.2 is hydrogen, methyl or ethyl; wherein R.sub.3 is hydrogen, fluoro, chloro, bromo, nitro and -CF.sub.3 ; and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, 2,6-difluorophenyl, and 2-pyridyl, are prepared by treating a hydrazino compound of the formula: ##STR2## with a carbonyl compound II: ##STR3## wherein R.sub.1 is defined as above, and R', R" are alkyl of 1 to 3 carbon atoms, inclusive, or the group ##STR4## is a cyclic acetal, such as ##STR5## to give a compound of formula III: ##STR6## wherein R.sub.1, R.sub.2, R.sub.3, R', R" and Ar are defined as above, and cyclizing compound III to give the compound IV above.Compounds III and IV, including the pharmacologically acceptable acid addition salt of these compounds, have sedative, anxiolytic and muscle-relaxing activity and can be used for the treatment of anxieties or muscle strains of mammals, including man.

Abstract: Compounds of the formula IV ##STR1## wherein R is hydrogen or alkyl of 1 or 2 carbon atoms; wherein R.sub.1 is alkyl of 1 to 3 carbon atoms, inclusive; or ##STR2## is a 2-cycloalkenylene ring of 5 or 6 carbon atoms; wherein R.sub.2 is hydrogen, methyl or ethyl; wherein R.sub.3 is hydrogen, fluoro, chloro, bromo, nitro and --CF.sub.3 ; and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, 2,6-difluorophenyl, and 2-pyridyl, are prepared by treating a hydrazino compound of the formula: ##STR3## wherein Ar and R.sub.3 are defined as above, with a dicarbonyl compound II: ##STR4## and cyclizing the resulting compound III to give the compound IV above. Compound IV, including the pharmacologically acceptable acid addition salt of these compounds, have sedative, anxiolytic and muscle-relaxing activity and can be used for the treatment of anxieties or muscle strains of mammals, including man.