Patents by Inventor Gerald P. Hirsch

Gerald P. Hirsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5593714
    Abstract: Foods and food ingredients are sterilized and preserved by the application of pressure of 250 KPa (25,000 psi) for 5 days. Some seafood requires maintenance of pressure for the duration of storage. For most fruits and vegetables ripening is stopped by the pressure treatment and packaged products can be stored without refrigeration for at least 6 months. Because no heat is used foods retain much of their firmness and texture.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: January 14, 1997
    Inventor: Gerald P. Hirsch
  • Patent number: 5430064
    Abstract: This invention concerns novel safe compositions containing as an active antioxidant or antiinflammatory agent and thiol-repleting agent, the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, and novel methods employing the compositions for treating or ameliorating symptoms of human immunodeficiency virus infection and AIDS, such as weight loss, increased red cell sedimentation, and leukoplakia; novel methods employing the compositions for treating or inhibiting symptoms resulting from nutritional deficiencies of methionine; and novel methods employing the compositions for inhibiting or preventing triglyceride elevation due to low dose methionine consumption. The compounds include the methionine hydroxy analogs, as well as compounds having the structural formula I:CH.sub.3 S(CH.sub.2).sub.2 CH(NH.sub.2)--COOHl-, dl- or d- formand pharmaceutically acceptable N- (mono- and di-carboxylic acid) acyl derivatives and alkyl esters thereof.
    Type: Grant
    Filed: March 4, 1994
    Date of Patent: July 4, 1995
    Inventors: Gerald P. Hirsch, Robert K. Bayless
  • Patent number: 5292773
    Abstract: This invention concerns novel safe compositions containing as an active antioxidant or antiinflammatory agent and thiol-repleting agent, the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, and novel methods employing the compositions for treating or amelio-rating symptoms of human immunodeficiency virus infection and AIDS, such as weight loss, increased red cell sedimentation, and leukoplakia; novel methods employing the compositions for treating or inhibiting symptoms resulting from nutritional deficiencies of methionine; and novel methods employing the compositions for inhibiting or preventing triglyceride elevation due to low dose methionine consumption. The compounds include the methionine hydroxy analogs, as well as compounds having the structural formula ##STR1## 1-, dl- or d- form and pharmaceutically acceptable N- (mono- and di-carboxylic acid) acyl derivatives and alkyl esters thereof.
    Type: Grant
    Filed: March 2, 1992
    Date of Patent: March 8, 1994
    Inventors: Gerald P. Hirsch, Robert K. Bayless
  • Patent number: 5084482
    Abstract: This invention concerns novel methods employing compositions containing as an active antioxidant or antiinflammatory agent the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, for treating or inhibiting inflammatory ischemic, thrombotic and cholesterolemic disease response in a subject. The compounds include the methionine hydroxy analogs, as well as compounds having the structural formula I: ##STR1## and pharmaceutically acceptable N-(mono- and di-carboxylic acid) acyl derivatives and alkyl esters thereof, where n is an integer from 1 to 3.
    Type: Grant
    Filed: April 10, 1990
    Date of Patent: January 28, 1992
    Assignee: The Lithox Corporation
    Inventors: Gerald P. Hirsch, Robert K. Bayless
  • Patent number: 5053429
    Abstract: This invention concerns novel methods employing compositions containing as an active antioxidant or antiinflammatory agent the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, for treating or inhibiting inflammation and inflammatory pain in a subject. The compounds include the methionine hydroxy analogs, as well as compounds having the structural formula I: ##STR1## and pharmaceutically acceptable N-(mono- and di-carboxylic acid) acyl derivatives and alkyl esters thereof, where n is an integer from 1 to 3.
    Type: Grant
    Filed: February 21, 1990
    Date of Patent: October 1, 1991
    Assignee: The Lithox Corporation, Inc.
    Inventors: Gerald P. Hirsch, Robert K. Bayless
  • Patent number: 4927850
    Abstract: This invention concerns novel dietary or therapeutic antioxidant compositions containing as the active agent the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, and novel methods employing the compositions for inhibiting inflammatory symptoms of respiratory disease. The compounds include the methionine hydroxy analog, the S-methyl methionine analog, and methionine compounds having the structural formula I ##STR1## and pharmaceutically acceptable N- (mono- and dicarboxylic acid) acyl derivatives and alkyl esters thereof, where n is an integer from 1 to 3.
    Type: Grant
    Filed: April 8, 1988
    Date of Patent: May 22, 1990
    Inventors: Robert K. Bayless, Gerald P. Hirsch
  • Patent number: 4902718
    Abstract: This invention concerns novel calcium normalizing compositions containing as the active agent the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, and novel methods employing the compositions for normalizing or controlling calcium metabolism. The compounds include the methionine hydroxy analog, the S-methyl methionine analog, and methionine compounds having the structural formula I ##STR1## and pharmaceutically acceptable N- (mono- and dicarboxylic acid) acyl derivatives and alkyl esters thereof, where in is an integer from 1 to 3.
    Type: Grant
    Filed: April 8, 1988
    Date of Patent: February 20, 1990
    Inventors: Robert K. Bayless, Gerald P. Hirsch, Sandra S. Kern
  • Patent number: 4199022
    Abstract: This invention relates to an improved method for freezing red blood cells, ther living cells, or tissues with improved subsequent survival, wherein constant-volume freezing is utilized that results in significantly improved survival compared with constant-pressure freezing; optimization is attainable through the use of different vessel geometries, cooling baths and warming baths, and sample concentrations.
    Type: Grant
    Filed: December 8, 1978
    Date of Patent: April 22, 1980
    Assignee: The United States of America as represented by the Department of Energy
    Inventors: Selim M. Senkan, Gerald P. Hirsch