Patents by Inventor Gerald P. Polli

Gerald P. Polli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110144144
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Application
    Filed: October 18, 2010
    Publication date: June 16, 2011
    Applicant: ABBOTT GMBH & CO. KG
    Inventors: Gregory P. KUSHLA, Jin-Wang LAI, Gerald P. POLLI
  • Patent number: 7833547
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: November 16, 2010
    Assignee: Abbott GmbH & Co. KG
    Inventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Patent number: 6599531
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: July 29, 2003
    Assignee: Knoll Pharmaceutical Company
    Inventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Publication number: 20030068368
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Application
    Filed: December 21, 2001
    Publication date: April 10, 2003
    Applicant: Knoll Pharmaceuticals
    Inventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Publication number: 20020127274
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Application
    Filed: December 21, 2001
    Publication date: September 12, 2002
    Applicant: BASF Corporation
    Inventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Publication number: 20020127275
    Abstract: Provided herein are slow release pharmaceutical compositions and methods of preparing slow release pharmaceutical compositions comprising mixing an unhydrated cellulose polymer with a hydrophobic substance to form a dry mixture; adding a granulating liquid to the dry mixture to form a wet mixture; and drying the wet mixture to obtain a blend suitable for use in a slow release pharmaceutical composition. The methods may be carried-out in the absence of a melting step for the hydrophobic substance. Also provided herein is a slow release composition comprising a cellulose polymer and a hydrophobic compound wherein the composition is provided in the substantial absence of a molecular coordination complex formed between the cellulose polymer and the hydrophobic substance. The slow release compositions may comprise a cellulose polymer and a hydrophobic compound in the substantial absence of a higher aliphatic alcohol.
    Type: Application
    Filed: January 11, 2002
    Publication date: September 12, 2002
    Applicant: BASF Corporation
    Inventors: Bin Bin Chang, Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Publication number: 20020110595
    Abstract: Provided herein are slow release pharmaceutical compositions and methods of preparing slow release pharmaceutical compositions comprising mixing an unhydrated cellulose polymer with a hydrophobic substance to form a dry mixture; adding a granulating liquid to the dry mixture to form a wet mixture, and drying the wet mixture to obtain a blend suitable for use in a slow release pharmaceutical composition. The methods may be carried-out in the absence of a melting step for the hydrophobic substance. Also provided herein is a slow release composition comprising a cellulose polymer and a hydrophobic compound wherein the composition is provided in the substantial absence of a molecular coordination complex formed between the cellulose polymer and the hydrophobic substance. The slow release compositions may comprise a cellulose polymer and a hydrophobic compound in the substantial absence of a higher aliphatic alcohol.
    Type: Application
    Filed: January 11, 2002
    Publication date: August 15, 2002
    Applicant: BASF Corporation
    Inventors: Bin Bin Chang, Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Patent number: 6361794
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Grant
    Filed: June 10, 1997
    Date of Patent: March 26, 2002
    Assignee: BASF Corporation
    Inventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Patent number: 6348216
    Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.
    Type: Grant
    Filed: June 10, 1997
    Date of Patent: February 19, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
  • Patent number: 5262167
    Abstract: A highly palatable, low moisture non-baked cholestyramine composition has cholestyramine in stable admixture with a suitable carrier. The carrier is made up of a grain or flour, sugars and starch binder, and may also contain flavorings, preservative, and an edible oil. The cholestyramine composition should not have more than 11.0% moisture by total weight and the optimal moisture content is not more than 2.0 to 4.0% by weight or lower. The composition may be in the form of coarse granules similar to granola or wheat germ, as well as croutons or chewable tablets which may be consumed without beverages or other food products.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: November 16, 1993
    Assignee: BASF Corporation
    Inventors: Raju V. K. Vegesna, Ashok Y. Gore, Gerald P. Polli
  • Patent number: 3974272
    Abstract: Palatable oral coacervate compositions containing Cholestyramine and a Modified Gum selected from the group consisting of hydrophilic colloid of cellulosive material and charged anionic gum in an aqueous medium.
    Type: Grant
    Filed: January 25, 1974
    Date of Patent: August 10, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Gerald P. Polli, Clyde E. Shoop