Patents by Inventor Gerald P. Polli
Gerald P. Polli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110144144Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: ApplicationFiled: October 18, 2010Publication date: June 16, 2011Applicant: ABBOTT GMBH & CO. KGInventors: Gregory P. KUSHLA, Jin-Wang LAI, Gerald P. POLLI
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Patent number: 7833547Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: GrantFiled: December 16, 2004Date of Patent: November 16, 2010Assignee: Abbott GmbH & Co. KGInventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Patent number: 6599531Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: GrantFiled: December 21, 2001Date of Patent: July 29, 2003Assignee: Knoll Pharmaceutical CompanyInventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Publication number: 20030068368Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: ApplicationFiled: December 21, 2001Publication date: April 10, 2003Applicant: Knoll PharmaceuticalsInventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Publication number: 20020127274Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: ApplicationFiled: December 21, 2001Publication date: September 12, 2002Applicant: BASF CorporationInventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Publication number: 20020127275Abstract: Provided herein are slow release pharmaceutical compositions and methods of preparing slow release pharmaceutical compositions comprising mixing an unhydrated cellulose polymer with a hydrophobic substance to form a dry mixture; adding a granulating liquid to the dry mixture to form a wet mixture; and drying the wet mixture to obtain a blend suitable for use in a slow release pharmaceutical composition. The methods may be carried-out in the absence of a melting step for the hydrophobic substance. Also provided herein is a slow release composition comprising a cellulose polymer and a hydrophobic compound wherein the composition is provided in the substantial absence of a molecular coordination complex formed between the cellulose polymer and the hydrophobic substance. The slow release compositions may comprise a cellulose polymer and a hydrophobic compound in the substantial absence of a higher aliphatic alcohol.Type: ApplicationFiled: January 11, 2002Publication date: September 12, 2002Applicant: BASF CorporationInventors: Bin Bin Chang, Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Publication number: 20020110595Abstract: Provided herein are slow release pharmaceutical compositions and methods of preparing slow release pharmaceutical compositions comprising mixing an unhydrated cellulose polymer with a hydrophobic substance to form a dry mixture; adding a granulating liquid to the dry mixture to form a wet mixture, and drying the wet mixture to obtain a blend suitable for use in a slow release pharmaceutical composition. The methods may be carried-out in the absence of a melting step for the hydrophobic substance. Also provided herein is a slow release composition comprising a cellulose polymer and a hydrophobic compound wherein the composition is provided in the substantial absence of a molecular coordination complex formed between the cellulose polymer and the hydrophobic substance. The slow release compositions may comprise a cellulose polymer and a hydrophobic compound in the substantial absence of a higher aliphatic alcohol.Type: ApplicationFiled: January 11, 2002Publication date: August 15, 2002Applicant: BASF CorporationInventors: Bin Bin Chang, Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Patent number: 6361794Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: GrantFiled: June 10, 1997Date of Patent: March 26, 2002Assignee: BASF CorporationInventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Patent number: 6348216Abstract: Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler selected from the group consisting of microcrystalline cellulose and powdered cellulose; a disintegrant selected from the group consisting of croscarmellose sodium, crospovidone, and sodium starch glycolate; a binder consisting of an akylhydroxy methylcellulose; a starch; and a lubricant.Type: GrantFiled: June 10, 1997Date of Patent: February 19, 2002Assignee: Knoll Pharmaceutical CompanyInventors: Gregory P. Kushla, Jin-Wang Lai, Gerald P. Polli
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Patent number: 5262167Abstract: A highly palatable, low moisture non-baked cholestyramine composition has cholestyramine in stable admixture with a suitable carrier. The carrier is made up of a grain or flour, sugars and starch binder, and may also contain flavorings, preservative, and an edible oil. The cholestyramine composition should not have more than 11.0% moisture by total weight and the optimal moisture content is not more than 2.0 to 4.0% by weight or lower. The composition may be in the form of coarse granules similar to granola or wheat germ, as well as croutons or chewable tablets which may be consumed without beverages or other food products.Type: GrantFiled: December 20, 1990Date of Patent: November 16, 1993Assignee: BASF CorporationInventors: Raju V. K. Vegesna, Ashok Y. Gore, Gerald P. Polli
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Patent number: 3974272Abstract: Palatable oral coacervate compositions containing Cholestyramine and a Modified Gum selected from the group consisting of hydrophilic colloid of cellulosive material and charged anionic gum in an aqueous medium.Type: GrantFiled: January 25, 1974Date of Patent: August 10, 1976Assignee: Merck & Co., Inc.Inventors: Gerald P. Polli, Clyde E. Shoop