Patents by Inventor Gerald Raul Kovacs

Gerald Raul Kovacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusogenic, self-propagating blebs as immunogenic compositions
    Patent number: 7541038
    Abstract: Self-propagating, fusogenic blebs are produced from cells infected with a population of Venezuelan Equine Encephalitis virus replicon particles (VRP). The self-propagating, fusogenic nature of the blebs is derived from expression of heterologous genes encoding viral fusion proteins that are incorporated into the replication defective replicon particles. The resulting blebs can be harvested from supernatants of cells displaying severe cytopathic effects. The blebs are used to make immunogenic compositions and devise methods of immunizing mammals against paramyxoviruses such as parainfluenza virus type 3.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: June 2, 2009
    Assignee: Wyeth Holdings Corporation
    Inventors: Gerald Raul Kovacs, Xiaoyan Mo, Nikolaos Vasilakis, Sangeeta Bhargava, Timothy Joseph Zamb, Stephen Alexander Udem