Patents by Inventor Gerald Stubbs

Gerald Stubbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic plants expressing disassembly deficient viral coat proteins
    Patent number: 5723750
    Abstract: The present invention provides a method for protecting plants against infection by pathogenic plant viruses comprising administering to the plant a nucleic acid, encoding a pathogenic plant virus protein, containing substitutions in the genetic sequence which result in the replacement of amino acids having carboxylate side chains with uncharged amino acids and which have the phenotypic effect of displacing wild type coat proteins in a wild type virus and inhibiting the ability of the wild type virus to disassemble under conditions whereby the nucleic acid is expressed as a mutant coat protein within the plant. Also provided is a nucleic acid, encoding a pathogenic plant virus protein, containing substitutions in the genetic sequence which result in the replacement of amino acids having carboxylate side chains with uncharged amino acids and which have the phenotypic effect of displacing wild type coat proteins in a wild type virus and inhibiting the ability of the wild type virus to disassemble.
    Type: Grant
    Filed: January 12, 1995
    Date of Patent: March 3, 1998
    Assignees: Vanderbilt University, Univ. of Maryland Biotechnology Institute
    Inventors: Gerald Stubbs, James N. Culver