Patents by Inventor Gerald T. Nepon

Gerald T. Nepon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic probe for diabetes type I predisposition
    Patent number: 5039606
    Abstract: An oligonucleotide probe for diagnosing predeposition or susceptibility to type I diabetes, capable of specifically hybridizing with the gene sequence3'-GCGGGCRARGRGGGGRGCAG-5'or5'-CGCCCGATACACCCCACGTC-3'wherein A is adenine, C is cytosine, G is guanine, T is thymine, and R is thymine or uracil. The probe may include at least 15 sequential nucleotides selected from the sequence5'-GCCCGATACACCCCCACGT-3'or3'-CGGGCRARGRGGGGGRGCA-5'The probe may be labeled with a detectable marker, such as an enzyme or biotin, and may be supplied in a diagnostic kit in combination with: a substratum capable of absorbing DNA or cells, a restriction enzyme, and/or a detergent.
    Type: Grant
    Filed: October 29, 1987
    Date of Patent: August 13, 1991
    Assignee: Virginia Mason Research Center
    Inventor: Gerald T. Nepon