Patents by Inventor Geraldine C. Harriman

Geraldine C. Harriman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRIAZOLE ACC INHIBITORS AND USES THEREOF
    Publication number: 20200017519
    Abstract: The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: April 24, 2019
    Publication date: January 16, 2020
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • ESTER ACC INHIBITORS AND USES THEREOF
    Publication number: 20200010478
    Abstract: The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: January 24, 2019
    Publication date: January 9, 2020
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • ACC INHIBITOR COMBINATION THERAPY FOR THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE
    Publication number: 20190381045
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a non-alcoholic fatty liver disease using an ACC inhibitor alone or with one or more additional therapeutic agents.
    Type: Application
    Filed: May 13, 2019
    Publication date: December 19, 2019
    Inventors: Geraldine C. Harriman, H. James Harwood, Rosana Kapeller-Libermann, William F. Westlin
  • PYRAZOLE ACC INHIBITORS AND USES THEREOF
    Publication number: 20190375759
    Abstract: The present invention provides pyrazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: January 3, 2019
    Publication date: December 12, 2019
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof
    Patent number: 10487090
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: November 26, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Jon P. Lawson, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Xiaotian Wang, Xiaowei Yang
  • ACC inhibitors and uses thereof
    Patent number: 10472374
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: November 12, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Sathesh Bhat, Jeremy Robert Greenwood, Geraldine C. Harriman, James Harwood, Craig E. Masse
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20190330224
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 27, 2018
    Publication date: October 31, 2019
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190284194
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 30, 2019
    Publication date: September 19, 2019
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190248810
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: February 8, 2019
    Publication date: August 15, 2019
    Inventors: Markus Dahlgren, Jeremy Robert Greenwood, Geraldine C. Harriman, Joshua Jahmil Kennedy-Smith, Craig E. Masse, Donna L. Romero, Mee Shelley, Ronald T. Wester
  • Triazole ACC inhibitors and uses thereof
    Publication number: 20190241582
    Abstract: The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: August 20, 2018
    Publication date: August 8, 2019
    Inventors: Shomir Gjosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20190225623
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: December 12, 2018
    Publication date: July 25, 2019
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • TYK2 inhibitors and uses thereof
    Patent number: 10323036
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: June 18, 2019
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TYK2 inhibitors and uses thereof
    Patent number: 10253046
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: April 9, 2019
    Assignee: Nimbus Lakshmi
    Inventors: Markus Dahlgren, Jeremy Robert Greenwood, Geraldine C. Harriman, Joshua Jahmil Kennedy-Smith, Craig E. Masse, Donna L. Romero, Mee Shelley, Ronald T. Wester
  • ACC inhibitors and uses thereof
    Patent number: 10208063
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 10208044
    Abstract: The present invention provides for compounds of formula I as acetyl-CoA carboxylase (ACC) inhibitors. The ACC inhibitors are useful for the prevention or treatment of metabolic syndrome, including obesity, dyslipidemia and hyperlipidemia in humans. The inhibitor compounds are also capable of inhibiting the ACC enzyme found in plants, parasites and bacteria.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • PESTICIDAL COMPOSITIONS AND USES THEREOF
    Publication number: 20190040078
    Abstract: Provided herein are compounds that exhibit activity as fungicides and are useful, for example, in methods for the control of fungal pathogens in plants and can be applied to said plants in a variety of ways.
    Type: Application
    Filed: July 9, 2018
    Publication date: February 7, 2019
    Inventors: Jennifer Lynn Bennett, Karen C. Fitzsimmons, Shomir Ghosh, Jeremy Robert Greenwood, William P. Haakenson, JR., Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Barry J. Shortt, Urszula J. Slomczynska, Jeffrey Michael Stein
  • TYK2 inhibitors and uses thereof
    Patent number: 10196390
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: February 5, 2019
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20190016732
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: March 9, 2018
    Publication date: January 17, 2019
    Inventors: Sathesh Bhat, Jeremy Robert Greenwood, Geraldine C. Harriman, James Harwood, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 10179793
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: January 15, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Jeremy Robert Greenwood
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20180354949
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: June 13, 2018
    Publication date: December 13, 2018
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren, Sayan Mondal, Shaughnessy Robinson