Patents by Inventor Gerarado A. Zapata

Gerarado A. Zapata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody fragment-polymer conjugates and humanized anti-IL-8 monoclonal antibodies
    Patent number: 6870033
    Abstract: Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous polymer, wherein the apparent size of the conjugate is at least about 500 kD. The conjugate exhibits substantially improved half-life, mean residence time, and/or clearance rate in circulation as compared to the underivatized parental antibody fragment.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: March 22, 2005
    Assignee: Genentech, Inc.
    Inventors: Vanessa Hsei, Iphigenia Koumenis, Steven R. Leong, Leonard G. Presta, Zahra Shahrokh, Gerarado A. Zapata