Patents by Inventor Gerard Alaux

Gerard Alaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY
    Publication number: 20080089936
    Abstract: The invention concerns a novel formulation for prolonged release of an active principle having a pH-dependent solubility. The inventive formulation comprises a matrix support based on hydrophilic polymer containing a specific dose of active principle, and further comprises one or more acidifying agents in the form of an acid salt of an organic acid.
    Type: Application
    Filed: December 3, 2007
    Publication date: April 17, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Gerard ALAUX, Frederic ANDRE, Gareth LEWIS, Veronique SERRE
  • Pharmaceutical Composition in the Form of a Gastric-Resident Tablet Containing an Active Principle
    Publication number: 20070190140
    Abstract: The disclosure concerns a pharmaceutical composition in the form of a gastric resident matrix tablet, comprising an active principle, characterized in that when contacted with an environment representing gastric fluid, it increases after 15 minutes in volume, by a swelling of at least 200%.
    Type: Application
    Filed: February 16, 2007
    Publication date: August 16, 2007
    Applicant: sanofi-aventis
    Inventors: Gerard Alaux, Estelle Chouin, Nathalie Dufresne-Arokiassamy
  • Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
    Publication number: 20060159744
    Abstract: The present invention relates to timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period, according to a profile of dissolution characterized in that it comprises two release pulses, the first being immediate (lasting up to 30 minutes) and the second being delayed by a fixed time (this fixed time being between 50 and 200 minutes).
    Type: Application
    Filed: March 21, 2006
    Publication date: July 20, 2006
    Applicant: Sanofi-Aventis
    Inventors: Gerard Alaux, Frederic Andre, Jean Ducassou, Gareth Lewis
  • Pharmaceutical composition with gastric residence and controlled release
    Patent number: 6861072
    Abstract: The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterized in that it comprises two or three layers and contains (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: March 1, 2005
    Assignee: Sanofi-Synthelabo
    Inventors: Gérard Alaux, Frédéric Andre, Alain Cuine, Gareth Lewis
  • Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
    Publication number: 20040258750
    Abstract: Timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period according to a profile of dissolution comprising two release pulses, the first being immediate and the second being delayed by a fixed time after administration.
    Type: Application
    Filed: April 6, 2004
    Publication date: December 23, 2004
    Inventors: Gerard Alaux, Frederic Andre, Jean Ducassou, Gareth Lewis
  • Controlled-release dosage forms comprising zolpidem or a salt thereof
    Patent number: 6514531
    Abstract: The present invention relates to controlled-release dosage forms of zolpidem or salts thereof adapted to release zolpidem over a predetermined time period, according to a biphasic profile of dissolution, where the first phase is an immediate release phase and the second phase is a prolonged release phase and particular embodiments thereof intended to avoid abuse.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: February 4, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Gérard Alaux, Gareth Lewis, Frédéric Andre