Patents by Inventor Gerard Byrne
Gerard Byrne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190005525Abstract: This disclosure relates generally to analyzing product promotions, and more particularly to system and method for determining effectiveness of product promotions. In one embodiment, a method is provided for determining an effectiveness of a promotion. The method includes receiving data related to sales and promotions for a plurality of products. The plurality of products includes a plurality of aggressor products and a plurality of victim products. The method further includes analyzing the data to determine a set of significant aggressor products for each of the plurality of victim products, assessing an impact of each of the set of significant aggressor products on a respective victim product, and determining the effectiveness of the promotion with respect to a product based on the data related to sales of the product under the promotion, and the impact of the product on each of one or more associated victim products.Type: ApplicationFiled: August 21, 2017Publication date: January 3, 2019Inventors: Paul Gerard Byrne, Srinidhi Srinivasan, Saju Ramachandran
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Patent number: 10006902Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: GrantFiled: June 23, 2014Date of Patent: June 26, 2018Assignee: SOPHION BIOSCIENCE A/SInventors: David Geraint Owen, Nicholas Gerard Byrne
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Patent number: 9456734Abstract: A scanner for an endoscope comprising: a scanning mechanism comprising a light transmitter and arranged to move the light transmitter to perform a scan; a lens system arranged to optically couple the light transmitter to a target during a scan; a first housing which houses at least a first portion of the lens system; a second housing which houses at least the fiber scanning mechanism; and a bendable joint joining the first and second housings such that in a scanning configuration the bendable joint joins the first and second housings so that optical elements in the first and second housings are aligned at a working separation, the bendable joint arranged to bend in response to insertion forces applied to the scanner during insertion of the scanner and revert to the scanning configuration in the absence of insertion forces.Type: GrantFiled: October 12, 2011Date of Patent: October 4, 2016Assignee: OPTISCAN PTY LTDInventors: Christopher Gerard Byrne, Robert Alan Pattie
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Publication number: 20160054298Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: ApplicationFiled: June 23, 2014Publication date: February 25, 2016Inventors: David Geraint Owen, Nicholas Gerard Byrne
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Publication number: 20150068925Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: ApplicationFiled: June 23, 2014Publication date: March 12, 2015Inventors: David Geraint Owen, Nicholas Gerard Byrne
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Patent number: 8759017Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: GrantFiled: May 2, 2013Date of Patent: June 24, 2014Assignee: Xention LimitedInventors: David Geraint Owen, Nicholas Gerard Byrne
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Publication number: 20130288289Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: ApplicationFiled: May 2, 2013Publication date: October 31, 2013Inventors: David Geraint Owen, Nicholas Gerard Byrne
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Publication number: 20130274597Abstract: A scanner for an endoscope comprising: a scanning mechanism comprising a light transmitter and arranged to move the light transmitter to perform a scan; a lens system arranged to optically couple the light transmitter to a target during a scan; a first housing which houses at least a first portion of the lens system; a second housing which houses at least the fibre scanning mechanism; and a bendable joint joining the first and second housings such that in a scanning configuration the bendable joint joins the first and second housings so that optical elements in the first and second housings are aligned at a working separation, the bendable joint arranged to bend in response to insertion forces applied to the scanner during insertion of the scanner and revert to the scanning configuration in the absence of insertion forces.Type: ApplicationFiled: October 12, 2011Publication date: October 17, 2013Applicant: OPTISCAN PTY LTDInventors: Christopher Gerard Byrne, Robert Alan Pattie
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Patent number: 8449825Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: GrantFiled: November 5, 2010Date of Patent: May 28, 2013Assignee: Xention LimitedInventors: David Geraint Owen, Nicholas Gerard Byrne
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Patent number: 7920312Abstract: A scanning apparatus and method, the apparatus comprising a light transmitter, a mount for supporting the light transmitter located remotely from its exit tip, a drive for driving the light transmitter to vibrate resonantly in a first direction and to vibrate non-resonantly in a second direction orthogonal to the first direction, and a synchronizer for synchronizing vibration of the light transmitter in the first and second directions so that the exit tip of the light transmitter executes a scan pattern. The drive applies a driving force to the light transmitter between the mount and the exit tip.Type: GrantFiled: September 13, 2007Date of Patent: April 5, 2011Assignee: Optiscan Pty Ltd.Inventors: Gavan Edmund Rosman, Bradley Charles Jones, Robert Alan Pattie, Christopher Gerard Byrne
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Publication number: 20110048939Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: ApplicationFiled: November 5, 2010Publication date: March 3, 2011Applicant: XENTION LIMITEDInventors: David Geraint Owen, Nicholas Gerard Byrne
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Patent number: 7846389Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on inn channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: GrantFiled: May 20, 2005Date of Patent: December 7, 2010Assignee: Xention LimitedInventors: David Geraint Owen, Nicholas Gerard Byrne
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Patent number: 7532375Abstract: A scanning method and apparatus, the apparatus comprising a fork with first and second forwardly extending tines and a rearwardly extending counterweight member, a mount for supporting the fork at a point between the tines and the counterweight member, and a drive for effecting relative vibration between the tines to provide a fast scan and for driving the fork to provide a slow scan transverse to the fast scan.Type: GrantFiled: September 23, 2005Date of Patent: May 12, 2009Assignees: Hoya Corporation, Optiscan Pty LtdInventors: Gavan Edmund Rosman, Christopher Gerard Byrne, Robert Alan Pattie
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Publication number: 20090015894Abstract: A scanning apparatus and method, the apparatus comprising a light transmitter, a mount for supporting the light transmitter located remotely from its exit tip, a drive for driving the light transmitter to vibrate resonantly in a first direction and to vibrate non-resonantly in a second direction orthogonal to the first direction, and a synchronizer for synchronizing vibration of the light transmitter in the first and second directions so that the exit tip of the light transmitter executes a scan pattern. The drive applies a driving force to the light transmitter between the mount and the exit tip.Type: ApplicationFiled: September 13, 2007Publication date: January 15, 2009Applicant: OPTISCAN PTY LTDInventors: Gavan Edmund Rosman, Bradley Charles Jones, Robert Alan Pattie, Christopher Gerard Byrne
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Patent number: 7384733Abstract: The invention provides a novel development of the conventional patch clamp technique for measurement of whole cell electrical activity. The invention provides for one or more cell or cells to be suspended in a liquid medium at a liquid/air interface (by virtue of the effect of surface tension at the interface) whereby the cell or cells are accessible at the interface to a microstructure electrode (such as a pipette tip) to which a cell can attach to form an electrical seal, for the purpose of whole cell voltage clamp recording. According to the invention the electrode can be caused to form a high resistance electrical seal with a cell suspended in the liquid at the liquid/air interface without the need to press the cell against a solid support surface. The invention also provides apparatus for carrying out the interface patch clamp technique and control logic for operating a computer to carry out the interface patch clamp technique.Type: GrantFiled: December 6, 1999Date of Patent: June 10, 2008Assignee: Xention Discovery LimitedInventors: Nicholas Gerard Byrne, David Geraint Owen
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Patent number: 7294102Abstract: A position control apparatus for controlling position along an axis, comprising: an extensible member that can be extended and contracted along said axis, comprising shape memory alloy locatable to expand and contract along said axis, heating means for controlling said temperature of said shape memory alloy, and a feedback mechanism for controlling said heating means and responsive to variations in said position, wherein said position is controllable by means of said heating means and can be stabilized by means of said feedback mechanism.Type: GrantFiled: April 13, 2004Date of Patent: November 13, 2007Assignees: PENTAX Corporation, Optiscan PTY Ltd.Inventors: Bradley Charles Jones, Christopher Gerard Byrne, Johan Gosse Lemmens, Libin Ni
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Patent number: 7123790Abstract: A scanning apparatus and method, the apparatus comprising: a light transmission means (90) having an exit tip; first and second drive means (92,94) for resonantly driving the light transmission means (90) in orthogonal directions; wherein the first and second drive means (92,94) are operable to move the tip in an elliptical pattern while varying the eccentricity of the elliptical pattern, whereby a portion of the elliptical pattern having a centre on the minor axis of the elliptical pattern approximates—at least in appearance—a raster pattern.Type: GrantFiled: October 29, 2003Date of Patent: October 17, 2006Assignee: Optiscan Pty. Ltd.Inventors: Gavan Edmund Rosman, Christopher Gerard Byrne, Bradley Charles Jones
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Patent number: 6936462Abstract: The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.Type: GrantFiled: June 14, 1999Date of Patent: August 30, 2005Assignee: Xention Discovery LimitedInventors: David Geraint Owen, Nicholas Gerard Byrne
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Publication number: 20040220453Abstract: A position control apparatus for controlling position along an axis, comprising: an extensible member that can be extended and contracted along said axis, comprising shape memory alloy locatable to expand and contract along said axis, heating means for controlling said temperature of said shape memory alloy, and a feedback mechanism for controlling said heating means and responsive to variations in said position, wherein said position is controllable by means of said heating means and can be stabilized by means of said feedback mechanism.Type: ApplicationFiled: April 13, 2004Publication date: November 4, 2004Applicants: PENTAX Corporation, OPTISCAN PTY LTD.Inventors: Bradley Charles Jones, Christopher Gerard Byrne, Johan Gosse Lemmens, Libin Ni
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Patent number: 5852375Abstract: An integrated circuit has an I/O circuit that is connected to an I/O PAD. The I/O PAD may have greater voltage than the VDD associated with the integrated circuit so there is provided a switching circuit that is connected between the VDD and the I/O PAD. An output circuit is also provided that comprises n-channel transistors connected between the PAD and the ground. There is a cascode arrangement of p-channel transistors connected between the I/O PAD and VDD.Type: GrantFiled: February 7, 1997Date of Patent: December 22, 1998Assignee: Silicon Systems Research LimitedInventors: Timothy Gerard Byrne, Brian T. Morley