Patents by Inventor Gerard Damien

Gerard Damien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIQUID ORAL FORMULATION OF BUMETANIDE
    Publication number: 20220370390
    Abstract: The invention relates to a liquid oral formulation of bumetanide for the treatment of autism, more particularly for the improvement of the Autism Spectrum Disorder (ASD) core symptoms, tuberous sclerosis complex, fragile X syndrome, Rett syndrome, Down syndrome, cancer and particularly gliomas, spinal cord lesions, chronic pain, brain trauma, cerebrovascular infarcts, various types of epilepsies, and also acute lung injury such as pneumonias or Severe Acute Respiratory Disease due to Coronavirus-2 (SARS-CoV-2). Said formulation is especially designed for paediatric populations. The invention relates also to a posology for the administration of said liquid oral formulation.
    Type: Application
    Filed: October 31, 2020
    Publication date: November 24, 2022
    Applicant: NEUROCHLORE
    Inventors: Yehezkel BEN-ARI, Denis RAVEL, Gérard DAMIEN
  • Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7879842
    Abstract: ?-Crystalline form of ivabradine of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as bradycardics.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: February 1, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Delta D-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7879841
    Abstract: A ?d-crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: February 1, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Gamma d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7872001
    Abstract: A ?d-Crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: January 18, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • ?-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7867996
    Abstract: A ?-Crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: January 11, 2011
    Assignee: Les Laboratories Servier
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • ?d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7867995
    Abstract: A ?d-Crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: January 11, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • ?-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7867997
    Abstract: A ?-crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: January 11, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
    Patent number: 7867994
    Abstract: Process for the synthesis of ivabradine of formula (I): addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof. ? crystalline form of ivabradine hydrochloride. Medicinal products containing ? crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
    Type: Grant
    Filed: January 18, 2007
    Date of Patent: January 11, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Michel Lerestif, Jean-Pierre Lecouve, Jean-Claude Souvie, Daniel Brigot, Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Alpha crystalline form of strontium ranelate
    Patent number: 7745482
    Abstract: Alpha crystalline form of strontium ranelate of formula (I): characterised by its powder X-ray diffraction diagram and by a water content of from 22 to 24%. Medicinal products containing the same which are useful in the treatment of osteoporosis and arthrosis.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: June 29, 2010
    Assignee: Les Laboratoires Servier
    Inventors: Stephane Horvath, Isabelle Demuynck, Gerard Damien
  • Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20100041640
    Abstract: ?-Crystalline form of ivabradine of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as bradycardics.
    Type: Application
    Filed: October 21, 2009
    Publication date: February 18, 2010
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stéphane Horvath, Marie-Noëlle Auguste, Gérard Damien
  • Gamma-Crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20090318417
    Abstract: A ?-Crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Application
    Filed: August 27, 2009
    Publication date: December 24, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Beta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20090318416
    Abstract: A ?d-Crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Application
    Filed: August 27, 2009
    Publication date: December 24, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stéphane Horvath, Marie-Noëlle Auguste, Gérard Damien
  • Gamma d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20090318420
    Abstract: A ?d-Crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Application
    Filed: August 27, 2009
    Publication date: December 24, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stéphane Horvath, Marie-Noëlle Auguste, Gérard Damien
  • Delta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20090318419
    Abstract: A ?-crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Application
    Filed: August 27, 2009
    Publication date: December 24, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stéphane Horvath, Marie-Noëlle Auguste, Gérard Damien
  • Process for the synthesis and crystalline form agomelatine
    Patent number: 7544839
    Abstract: Process for the industrial synthesis and new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: June 9, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Souvie, Isaac Gonzalez-Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien
  • Process for the synthesis and crystalline form of agomelatine
    Patent number: 7498466
    Abstract: A process for the industrial synthesis and new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: March 3, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien
  • Process for the synthesis and crystalline form of agomelatine
    Patent number: 7498465
    Abstract: A process for the industrial synthesis and new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: March 3, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien
  • Alpha crystalline form of strontium ranelate
    Publication number: 20080312314
    Abstract: Alpha crystalline form of strontium ranelate of formula (I): characterised by its powder X-ray diffraction diagram and by a water content of from 22 to 24%. Medicinal products containing the same which are useful in the treatment of osteoporosis and arthrosis.
    Type: Application
    Filed: August 12, 2008
    Publication date: December 18, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stephane Horvath, Isabelle Demuynck, Gerard Damien
  • Alpha crystalline form of strontium ranelate
    Patent number: 7459568
    Abstract: Alpha crystalline form of strontium ranelate of formula (I): characterized by its powder X-ray diffraction diagram and by a water content of from 22 to 24%. Medicinal products containing the same which are useful in the treatment of osteoporosis and arthrosis.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: December 2, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Stéphane Horvath, Isabelle Demuynck, Gérard Damien
  • Delta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20080227771
    Abstract: A ?d-crystalline form of ivabradine hydrochloride of formula (I): characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
    Type: Application
    Filed: May 7, 2008
    Publication date: September 18, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Stephane Horvath, Marie-Noelle Auguste, Gerard Damien